A Novel Method for the Synthesis of (1,8-Dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)acetic Acids on Solid Phase

被引：6
作者：
Cravero, Raquel M. [1 ]
Luna, Liliana E. [1 ]
Barboza, Andrea V. [1 ]
机构：
[1] Univ Nacl Rosario Suipacha 531, Fac Ciencias Bioquim & Farmaceut, IQUIR Inst Quim Rosario, Rosario, Santa Fe, Argentina
来源：
SYNTHESIS-STUTTGART | 2011年 / 24期
关键词：
polycycles; tandem reactions; cycloadditions; Michael addition; solid-phase synthesis; SUPPORTED SYNTHESIS; DERIVATIVES; THIOACETALIZATION; XANTHONES; EFFICIENT;
D O I：
10.1055/s-0031-1289602
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report the first solid-phase synthesis of (1,8-dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)acetic acids via a tandem Michael-Michael cyclization with resin-bound propiolic acid as Michael acceptor and cyclohexanediones.
引用
收藏
页码：4027 / 4032
页数：6
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