Active Polymer Translocation through Flickering Pores

被引:59
作者
Cohen, Jack A. [1 ]
Chaudhuri, Abhishek [1 ,2 ]
Golestanian, Ramin [1 ]
机构
[1] Univ Oxford, Rudolf Peierls Ctr Theoret Phys, Oxford OX1 3NP, England
[2] Univ Sheffield, Dept Biomed Sci, Sheffield S10 2TN, S Yorkshire, England
基金
英国工程与自然科学研究理事会;
关键词
NANOPORE; DYNAMICS; MOLECULES; MEMBRANE;
D O I
10.1103/PhysRevLett.107.238102
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Single file translocation of a homopolymer through an active channel under the presence of a driving force is studied using Langevin dynamics simulation. It is shown that a channel with sticky walls and oscillating width could lead to significantly more efficient translocation as compared to a static channel that has a width equal to the mean width of the oscillating pore. The gain in translocation exhibits a strong dependence on the stickiness of the pore, which could allow the polymer translocation process to be highly selective.
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页数:5
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