Facile synthesis and self-assembly behaviour of pH-responsive degradable polyacetal dendrimers

被引：34

作者：

Huang, Da ^{[1
,2
]}

Yang, Fei ^{[1
,2
]}

Wang, Xing ^{[1
]}

Shen, Hong ^{[1
]}

You, Yezi ^{[3
]}

Wu, Decheng ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

[3] Univ Sci & Technol China, Dept Polymer Sci & Engn, CAS Key Lab Soft Matter Chem, Hefei 230026, Peoples R China

来源：

POLYMER CHEMISTRY | 2016年 / 7卷 / 40期

关键词：

DRUG-DELIVERY; CLICK CHEMISTRY; THIOL-ENE; NANOPARTICLES; DOXORUBICIN; EFFICIENT; THERAPY; SYSTEMS; CYCLODEXTRIN; CYTOTOXICITY;

D O I：

10.1039/c6py01511e

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Herein, we report the facile synthesis of a class of well-defined acid-labile polyacetal dendrimers, which can be easily functionalized by poly(ethylene glycol) or zwitterions and self-assemble into pH-responsive degradable micelles or nanofibers.

引用

页码：6154 / 6158

页数：5