Facile synthesis and self-assembly behaviour of pH-responsive degradable polyacetal dendrimers

被引:34
|
作者
Huang, Da [1 ,2 ]
Yang, Fei [1 ,2 ]
Wang, Xing [1 ]
Shen, Hong [1 ]
You, Yezi [3 ]
Wu, Decheng [1 ,2 ]
机构
[1] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] Univ Sci & Technol China, Dept Polymer Sci & Engn, CAS Key Lab Soft Matter Chem, Hefei 230026, Peoples R China
关键词
DRUG-DELIVERY; CLICK CHEMISTRY; THIOL-ENE; NANOPARTICLES; DOXORUBICIN; EFFICIENT; THERAPY; SYSTEMS; CYCLODEXTRIN; CYTOTOXICITY;
D O I
10.1039/c6py01511e
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Herein, we report the facile synthesis of a class of well-defined acid-labile polyacetal dendrimers, which can be easily functionalized by poly(ethylene glycol) or zwitterions and self-assemble into pH-responsive degradable micelles or nanofibers.
引用
收藏
页码:6154 / 6158
页数:5
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