Facile synthesis and self-assembly behaviour of pH-responsive degradable polyacetal dendrimers

被引:34
|
作者
Huang, Da [1 ,2 ]
Yang, Fei [1 ,2 ]
Wang, Xing [1 ]
Shen, Hong [1 ]
You, Yezi [3 ]
Wu, Decheng [1 ,2 ]
机构
[1] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] Univ Sci & Technol China, Dept Polymer Sci & Engn, CAS Key Lab Soft Matter Chem, Hefei 230026, Peoples R China
关键词
DRUG-DELIVERY; CLICK CHEMISTRY; THIOL-ENE; NANOPARTICLES; DOXORUBICIN; EFFICIENT; THERAPY; SYSTEMS; CYCLODEXTRIN; CYTOTOXICITY;
D O I
10.1039/c6py01511e
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Herein, we report the facile synthesis of a class of well-defined acid-labile polyacetal dendrimers, which can be easily functionalized by poly(ethylene glycol) or zwitterions and self-assemble into pH-responsive degradable micelles or nanofibers.
引用
收藏
页码:6154 / 6158
页数:5
相关论文
共 50 条
  • [1] Synthesis and Self-Assembly of the pH-Responsive Anionic Copolymers for Enhanced Doxorubicin-Loading Capacity
    Yi, Meijun
    Lu, Qian
    Zhao, Yuping
    Cheng, Chenqian
    Zhang, Shiping
    LANGMUIR, 2018, 34 (26) : 7877 - 7886
  • [2] pH-Responsive reversible self-assembly of gold nanoparticles into nanovesicles
    Fan, Chunfang
    Bian, Tong
    Shang, Lu
    Shi, Run
    Wu, Li-Zhu
    Tung, Chen-Ho
    Zhang, Tierui
    NANOSCALE, 2016, 8 (07) : 3923 - 3925
  • [3] pH-Responsive Self-Assembly by Molecular Recognition on a Macroscopic Scale
    Zheng, Yongtai
    Hashidzume, Akihito
    Harada, Akira
    MACROMOLECULAR RAPID COMMUNICATIONS, 2013, 34 (13) : 1062 - 1066
  • [4] Fabrication of zwitterionic and pH-responsive polyacetal dendrimers for anticancer drug delivery
    Wang, Yaqiang
    Huang, Da
    Wang, Xing
    Yang, Fei
    Shen, Hong
    Wu, Decheng
    BIOMATERIALS SCIENCE, 2019, 7 (08) : 3238 - 3248
  • [5] A facile strategy to fabricate a pH-responsive mesoporous silica nanoparticle end-capped with amphiphilic peptides by self-assembly
    Zhao, Fengfeng
    Zhang, Chen
    Zhao, Chenggui
    Gao, Wei
    Fan, Xiaobo
    Wu, Guoqiu
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2019, 179 : 352 - 362
  • [6] Polymer Directed Self-Assembly of pH-Responsive Antioxidant Nanoparticles
    Tang, Christina
    Amin, Devang
    Messersmith, Phillip B.
    Anthony, John E.
    Prad'homme, Robert K.
    LANGMUIR, 2015, 31 (12) : 3612 - 3620
  • [7] pH-Responsive porphyrin-silica nanoparticles conjugate via ionic self-assembly
    Fathalla, Maher
    Sinatra, Lutfan
    JOURNAL OF POROUS MATERIALS, 2021, 28 (01) : 183 - 189
  • [8] Synthesis and self-assembly of a dual thermal and pH-responsive ternary graft copolymer for sustained release drug delivery
    Li, Yinwen
    Zheng, Xiuwen
    Wu, Kun
    Lu, Mangeng
    RSC ADVANCES, 2016, 6 (04) : 2571 - 2581
  • [9] Computer Simulation Studies on the pH-Responsive Self-Assembly of Amphiphilic Carboxy-Terminated Polyester Dendrimers in Aqueous Solution
    Yu, Chunyang
    Ma, Li
    Li, Ke
    Li, Shanlong
    Liu, Yannan
    Liu, Lifen
    Zhou, Yongfeng
    Yan, Deyue
    LANGMUIR, 2017, 33 (01) : 388 - 399
  • [10] The synthesis, self-assembly and pH-responsive fluorescence enhancement of an alternating amphiphilic copolymer with azobenzene pendants
    Wu, Jiacheng
    Xu, Binbin
    Liu, Zhenghui
    Yao, Yuan
    Zhuang, Qixin
    Lin, Shaoliang
    POLYMER CHEMISTRY, 2019, 10 (29) : 4025 - 4030