Romania, a Harbour of HIV-1 Subtype F1: Where Are We after 33 Years of HIV-1 Infection?

被引：9

作者：

Preda, Madalina ^{[1
,2
]}

Manolescu, Loredana Cornelia Sabina ^{[1
,3
]}

机构：

[1] Carol Davila Univ Med & Pharm, Dept Microbiol Parasitol & Virol, Fac Midwives & Nursing, Bucharest 020021, Romania

[2] Marius Nasta Inst Pneumol, Res Dept, Bucharest 050159, Romania

[3] Inst Virol Stefan S Nicolau, Dept Virol, Bucharest 030304, Romania

来源：

VIRUSES-BASEL | 2022年 / 14卷 / 09期

关键词：

subtype F1; HIV/AIDS; HIV-1 infection in Romania; RESISTANCE MUTATIONS; DRUG-RESISTANCE; EPIDEMIC; USERS;

D O I：

10.3390/v14092081

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Infection with the human immunodeficiency virus (HIV) has been a major public health concern worldwide for more than 30 years, including in Romania. The F1 HIV-1 subtype was exported from Angola to Romania most probably because of the two countries' close political connections. Patients infected with HIV-1 via re-used and improperly sterilized injection equipment and through transfusions of unscreened blood, also known as the "Romanian cohort", were the most common type of HIV-1 infection in Romania in the early 1990s, when the virus's presence was recognized. Recently, subtype B started to increase in our country, mostly diagnosed in people using intravenous drugs or in men having sex with men. The evolution of the HIV-1 infection in Romania has been unique, with a dominance of the subtype F1, making it different from other countries in Europe.

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页数：9

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