Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic

被引：2
|
作者：
Mihalcin, Matus [1 ,2 ]
Husova, Libuse [3 ]
Vasickova, Petra [4 ]
Bena, Marcel [4 ]
Husa, Petr [1 ,2 ]
机构：
[1] Masaryk Univ, Fac Med, Dept Infect Dis, Kamenice 5, Brno 62500, Czech Republic
[2] Univ Hosp Brno, Dept Infect Dis, Jihlavska 20, Brno 62500, Czech Republic
[3] Ctr Cardiovasc & Transplant Surg Brno, Brno, Czech Republic
[4] Vet Res Inst, Brno, Czech Republic
来源：
ARCHIVES OF MEDICAL SCIENCE | 2022年 / 18卷 / 05期
关键词：
therapy; epidemiology; Czech Republic; Eastern Europe; hepatitis E; hepatitis E virus; viral zoonosis; E VIRUS;
D O I：
10.5114/aoms/152338
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction: The majority of hepatitis E ( HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. Methods: A retrospective analysis of 173 patients with HE. Results: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. Conclusions: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.
引用
收藏
页码：1395 / 1398
页数：4
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