Three new indole alkaloids from the leaves of Alstonia scholaris

被引：35

作者：

Zhou, H ^{[1
]}

He, HP ^{[1
]}

Luo, XD ^{[1
]}

Wang, YH ^{[1
]}

Yang, XW ^{[1
]}

Di, YT ^{[1
]}

Hao, XJ ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2005年 / 88卷 / 09期

关键词：

D O I：

10.1002/hlca.200590186

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three new akuamillan-type indole alkaloids, i.e., 5-methoxystrictamine (=methyl (5 beta,16R,19E)-5-methoxyakuammilan-17-oate; 1), methyl (16R,19E)-1,2-dihydro-16-(hydroxymethyl)-5-oxoakuammilan-17-oate (2), and methyl (2 beta 16R,19E)-4,5-didehydro-1,2-dihydro-2-hydroxy-16-(hydroxymethyl)akuammilan-4-ium-17-oate chloride (3), have been isolated from the leaves of Alstonia scholaris, together with ten known compounds. Their structures were determined by spectroscopic means. None of the constituents showed significant cytotoxic activity towards WT cells.

引用

页码：2508 / 2512

页数：5

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