EVOLUTION AND MEDICINE IN UNDERGRADUATE EDUCATION: A PRESCRIPTION FOR ALL BIOLOGY STUDENTS

被引:21
作者
Antolin, Michael F. [1 ]
Jenkins, Kristin P. [13 ]
Bergstrom, Carl T. [2 ]
Crespi, Bernard J. [3 ]
De, Subhajyoti [4 ]
Hancock, Angela [5 ]
Hanley, Kathryn A. [6 ]
Meagher, Thomas R. [7 ]
Moreno-Estrada, Andres [8 ]
Nesse, Randolph M. [9 ]
Omenn, Gilbert S. [10 ,12 ]
Stearns, Stephen C. [11 ]
机构
[1] Colorado State Univ, Dept Biol, Ft Collins, CO 80523 USA
[2] Univ Washington, Dept Biol, Seattle, WA 98195 USA
[3] Simon Fraser Univ, Dept Biol Sci, Burnaby, BC V5A 1S6, Canada
[4] Harvard Univ, Sch Publ Hlth, Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02115 USA
[5] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA
[6] New Mexico State Univ, Dept Biol, Las Cruces, NM 88003 USA
[7] Univ St Andrews, Sch Biol, St Andrews KY15 4RP, Fife, Scotland
[8] Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA
[9] Univ Michigan, Dept Psychiat, Ann Arbor, MI 48109 USA
[10] Univ Michigan, Sch Publ Hlth, Dept Internal Med, Ctr Computat Med & Bioinformat, Ann Arbor, MI 48109 USA
[11] Yale Univ, Dept Ecol & Evolutionary Biol, New Haven, CT 06520 USA
[12] Univ Michigan, Sch Publ Hlth, Ctr Computat Med & Bioinformat, Dept Human Genet, Ann Arbor, MI 48109 USA
[13] Natl Evolutionary Synth Ctr, Durham, NC 27705 USA
关键词
Biomedical research; evolution of disease; host-pathogen interactions; human genetics; medical practice; mismatch hypothesis; premedical curriculum; public health; science education; DEGENERATIVE DISEASES; ANTIBIOTIC-RESISTANCE; POPULATION-GENETICS; GLOBAL DISTRIBUTION; POSITIVE SELECTION; ASSOCIATION; VARIANT; CANCER; VIRUS; PIGMENTATION;
D O I
10.1111/j.1558-5646.2011.01552.x
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
The interface between evolutionary biology and the biomedical sciences promises to advance understanding of the origins of genetic and infectious diseases in humans, potentially leading to improved medical diagnostics, therapies, and public health practices. The biomedical sciences also provide unparalleled examples for evolutionary biologists to explore. However, gaps persist between evolution and medicine, for historical reasons and because they are often perceived as having disparate goals. Evolutionary biologists have a role in building a bridge between the disciplines by presenting evolutionary biology in the context of human health and medical practice to undergraduates, including premedical and preprofessional students. We suggest that students will find medical examples of evolution engaging. By making the connections between evolution and medicine clear at the undergraduate level, the stage is set for future health providers and biomedical scientists to work productively in this synthetic area. Here, we frame key evolutionary concepts in terms of human health, so that biomedical examples may be more easily incorporated into evolution courses or more specialized courses on evolutionary medicine. Our goal is to aid in building the scientific foundation in evolutionary biology for all students, and to encourage evolutionary biologists to join in the integration of evolution and medicine.
引用
收藏
页码:1991 / 2006
页数:16
相关论文
共 148 条
[21]   Resistance among Escherichia coli to sulphonamides and other antimicrobials now little used in man [J].
Bean, DC ;
Livermore, DM ;
Papa, I ;
Hall, LMC .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (05) :962-964
[22]  
Beardsley P.M., 2011, Evol. Educ. Outreach, V4, P603, DOI DOI 10.1007/S12052-011-0361-2
[23]  
Bergstrom C. T., 2007, EVOLUTION HLTH DIS, P122
[24]  
Bergstrom CT., 2011, EVOLUTION
[25]  
BRANSFORD J, 2000, PEOPLE LEARN BRAIN M, DOI [10.17226/9853, DOI 10.17226/9853]
[26]   Stress, testosterone, and the immunoredistribution hypothesis [J].
Braude, S ;
Tang-Martinez, Z ;
Taylor, GT .
BEHAVIORAL ECOLOGY, 1999, 10 (03) :345-350
[27]   Patterns of epistasis in RNA viruses: a review of the evidence from vaccine design [J].
Burch, CL ;
Turner, PE ;
Hanley, KA .
JOURNAL OF EVOLUTIONARY BIOLOGY, 2003, 16 (06) :1223-1235
[28]  
Burnet M., 1972, The Natural History of Infectious Disease
[29]  
Bynum W F, 1983, Gesnerus, V40, P43
[30]   Literature review: should antipyretic therapies routinely be administered to patient fever? [J].
Carey, Jane V. .
JOURNAL OF CLINICAL NURSING, 2010, 19 (17-18) :2377-2393