Preoperative cardiac assessment in liver transplant candidates

被引:12
作者
De Gasperi, Andrea [1 ]
Spagnolin, Gregorio [1 ]
Ornaghi, Martina [1 ]
Petro, Laura [1 ]
Biancofiore, Gianni [2 ]
机构
[1] ASST Grande Osped Metropolitano Niguarda, Serv Anesthesia Rianimaz 2, Milan, Italy
[2] Azienda Osped Univ Pisana, Transplant Anesthesia & Crit Care Unit, Univ Sch Med, Pisa, Italy
关键词
liver transplantation; preoperative cardiac assessment; coronary artery disease; cirrhotic cardiomyopathy; hepatopulmonary syndrome; portopulmonary syndrome; CORONARY-ARTERY-DISEASE; 6-MINUTE WALK TEST; CARDIOVASCULAR RISK-ASSESSMENT; SCIENTIFIC STATEMENT; FUNCTIONAL-CAPACITY; NONCARDIAC SURGERY; PORTOPULMONARY HYPERTENSION; TOMOGRAPHIC ANGIOGRAPHY; PREDICTS MORTALITY; VALVE-REPLACEMENT;
D O I
10.1016/j.bpa.2020.02.002
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
New and extended indications, older age, higher cardiovascular risk, and the long-standing cirrhosis-associated complications mandate specific skills for an appropriate preoperative assessment of the liver transplant (LT) candidate. The incidence of cardiac diseases (dysrhythmias, cardiomyopathies, coronary artery disease, valvular heart disease) are increasing among LT recipients: however, no consensus exists among clinical practice guidelines for cardiovascular screening and risk stratification. In spite of different "transplant center-centered protocols", basic "pillars" are common (electrocardiography, baseline echocardiography, functional assessment). Owing to intrinsic limitations, yields and relevance of noninvasive stress tests, under constant scrutiny even if used, are discussed, focusing the definition of the "high risk" candidate and exploring noninvasive imaging and new forms of stress imaging. The aim is to find an appropriate and rational stepwise algorithm. The final commitment is to select the right candidate for a finite resource, the graft, able to save (and change) lives. (C) 2020 Elsevier Ltd. All rights reserved.
引用
收藏
页码:51 / 68
页数:18
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