Viral RNA in Blood as Indicator of Severe Outcome in Middle East Respiratory Syndrome coronavirus Infection

被引:43
作者
Kim, So Yeon [1 ]
Park, Sun Jae [1 ]
Cho, Sook Young [1 ]
Cha, Ran-hui [1 ]
Jee, Hyeon-Gun [1 ]
Kim, Gayeon [1 ]
Shin, Hyoung-Shik [1 ]
Kim, Yeonjae [1 ]
Jung, Yu Mi [1 ]
Yang, Jeong-Sun [2 ]
Kim, Sung Soon [2 ]
Cho, Sung Im [3 ]
Kim, Man Jin [3 ]
Lee, Jee-Soo [3 ]
Lee, Seung Jun [3 ]
Seo, Soo Hyun [3 ]
Park, Sung Sup [3 ]
Seong, Moon-Woo [3 ]
机构
[1] Natl Med Ctr, Seoul, South Korea
[2] Korea Ctr Dis Control & Prevent, Cheongju, South Korea
[3] Seoul Natl Univ, Coll Med, Seoul, South Korea
关键词
CLINICAL-FEATURES; DISEASE;
D O I
10.3201/eid2210.160218
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We evaluated the diagnostic and clinical usefulness of blood specimens to detect Middle East respiratory syndrome coronavirus infection in 21 patients from the 2015 outbreak in South Korea. Viral RNA was detected in blood from 33% of patients at initial diagnosis, and the detection preceded a worse clinical course.
引用
收藏
页码:1813 / 1816
页数:4
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