A highly efficient three-component coupling of aldehyde, terminal alkyne, and amine via C-H activation catalyzed by reusable immobilized copper in organic-inorganic hybrid materials under solvent-free reaction conditions

被引：99

作者：

Li, Pinhua ^{[1
]}

Wang, Lei ^{[1
,2
]}

机构：

[1] Huaibei Coal Teachers Coll, Dept Chem, Huaibei 235000, Anhui, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON | 2007年 / 63卷 / 25期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/j.tet.2007.04.032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Recycling copper( I) immobilized on organic-inorganic hybrid material behaves as a very efficient heterogeneous catalyst in the three-component Mannich coupling reaction of aldehydes, terminal alkynes, and amines via C-H activation to afford the corresponding products in good to excellent yields under solvent-free reaction conditions. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：5455 / 5459

页数：5

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