Creutzfeldt-Jakob Disease Following Kidney Transplantation

被引:1
作者
Sharma, Neeraj [1 ]
Wang, Lin [2 ]
Namboodiri, Hima [3 ]
机构
[1] Univ Southern Calif, Dept Nephrol, Univ Southern Calif Transplant, Los Angeles, CA 90007 USA
[2] Univ Southern Calif, Div Nephrol & Hypertens, Los Angeles, CA 90007 USA
[3] Keck Sch Med, Internal Med, Los Angeles, CA USA
关键词
kidney transplantation; cns; opportunistic infections; creutzfeldt-jakob disease; prion disease; acute encephalopathy; ORGAN; CJD;
D O I
10.7759/cureus.21632
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Neurologic complications after kidney transplantation are frequent and related to immunosuppressive therapy and vintage dialysis time, including comorbidities such as diabetes, hypertension, and cardiovascular diseases. Creutzfeldt-Jakob disease (CJD) is a very rare and rapidly fatal neurodegenerative disorder. Kidney transplant recipients present with mixed and complex neuropsychiatric manifestations, which makes diagnosis challenging. This case highlights the importance of enhancing awareness of the clinical presentation and timely diagnosis of this rare, fatal neurodegenerative disorder.
引用
收藏
页数:4
相关论文
共 12 条
[1]  
[Anonymous], 2020, CREUTZFELDT JAKOB DI
[2]  
[Anonymous], 2019, Diagnostic criteria
[3]  
Appleby Brian S, 2018, Handb Clin Neurol, V153, P399, DOI 10.1016/B978-0-444-63945-5.00021-0
[4]   CREUTZFELDT-JAKOB-DISEASE AFTER LIVER-TRANSPLANTATION [J].
CREANGE, A ;
GRAY, F ;
CESARO, P ;
ADLEBIASSETTE, H ;
DUVOUX, C ;
CHERQUI, D ;
BELL, J ;
PARCHI, P ;
GAMBETTI, P ;
DEGOS, JD .
ANNALS OF NEUROLOGY, 1995, 38 (02) :269-272
[5]   Sporadic and familial CJD: classification and characterisation [J].
Gambetti, P ;
Kong, QZ ;
Zou, WQ ;
Parchi, P ;
Chen, SG .
BRITISH MEDICAL BULLETIN, 2003, 66 :213-+
[6]   Clinical trials for prion disease: difficult challenges, but hope for the future [J].
Geschwind, Michael D. .
LANCET NEUROLOGY, 2009, 8 (04) :304-306
[7]   Creutzfeldt-Jakob disease following corneal transplantation [J].
Hammersmith, KM ;
Cohen, EJ ;
Rapuano, CJ ;
Laibson, PR .
CORNEA, 2004, 23 (04) :406-408
[8]   Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada [J].
Ladogana, A ;
Puopolo, M ;
Croes, EA ;
Budka, H ;
Jarius, C ;
Collins, S ;
Klug, GM ;
Sutcliffe, T ;
Giulivi, A ;
Alperovitch, A ;
Delasnerie-Laupretre, N ;
Brandel, JP ;
Poser, S ;
Kretzschmar, H ;
Rietveld, I ;
Mitrova, E ;
Cuesta, JD ;
Martinez-Martin, P ;
Glatzel, M ;
Aguzzi, A ;
Knight, R ;
Ward, H ;
Pocchiari, M ;
van Duijn, CM ;
Will, RG ;
Zerr, I .
NEUROLOGY, 2005, 64 (09) :1586-1591
[9]   Neurologic complications after solid organ transplantation [J].
Marco, Senzolo ;
Cecilia, Ferronato ;
Patrizia, Burra .
TRANSPLANT INTERNATIONAL, 2009, 22 (03) :269-278
[10]   Investigation of Variant Creutzfeldt-Jakob Disease Implicated Organ or Tissue Transplantation in the United Kingdom [J].
Molesworth, Anna ;
Yates, Philip ;
Hewitt, Patricia E. ;
Mackenzie, Jan ;
Ironside, James W. ;
Galea, George ;
Ward, Hester J. T. .
TRANSPLANTATION, 2014, 98 (05) :585-589