Synthesis of 2-Amino-5-hydroxy-5-phosphonovaleric Acid

被引：0

作者：

Ragulin, V. V. ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Physiol Act Subst, Severnyi Proezd 1, Chernogolovka 142432, Russia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2018年 / 88卷 / 09期

基金：

俄罗斯基础研究基金会;

关键词：

AP acids; NMDA receptor antagonists; HO-AP5; 4-acetamido-4; 4-bis(ethyloxycarbonyl)butyraldehyde;

D O I：

10.1134/S1070363218090256

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of a new analog of 2-amino-5-phosphonovaleric acid (AP5), namely 2-amino-5-hydroxy-5-phosphonovaleric acid, by successive Michael addition of acetamidomalonic ester to acrolein and Abramov's phosphorylation of the aldehydes formed in situ was developed.

引用

页码：1915 / 1917

页数：3