Synthesis of 2-Amino-5-hydroxy-5-phosphonovaleric Acid

被引：0
|
作者：
Ragulin, V. V. [1 ]
机构：
[1] Russian Acad Sci, Inst Physiol Act Subst, Severnyi Proezd 1, Chernogolovka 142432, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2018年 / 88卷 / 09期
基金：
俄罗斯基础研究基金会;
关键词：
AP acids; NMDA receptor antagonists; HO-AP5; 4-acetamido-4; 4-bis(ethyloxycarbonyl)butyraldehyde;
D O I：
10.1134/S1070363218090256
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of a new analog of 2-amino-5-phosphonovaleric acid (AP5), namely 2-amino-5-hydroxy-5-phosphonovaleric acid, by successive Michael addition of acetamidomalonic ester to acrolein and Abramov's phosphorylation of the aldehydes formed in situ was developed.
引用
收藏
页码：1915 / 1917
页数：3
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