Hepatoblastoma of the adult: A systematic review of the literature

被引:13
作者
Celotti, Andrea [1 ]
D'Amico, Giuseppe [1 ]
Ceresoli, Marco [1 ]
Tomasoni, Matteo [1 ]
Raimondo, Stefano [1 ]
Baggi, Paolo [1 ]
Baiocchi, Gian Luca [1 ]
机构
[1] Univ Brescia, Dept Med & Surg Sci, Surg Clin, I-25123 Brescia, Italy
来源
SURGICAL ONCOLOGY-OXFORD | 2016年 / 25卷 / 03期
关键词
Hepatoblastoma; Hepatoblastoma of the adult; Liver tumor; MIXED MALIGNANT-TUMOR; HEPATOCELLULAR-CARCINOMA; RESECTED HEPATOBLASTOMA; YOUNG-ADULT; LIVER; RECURRENCE;
D O I
10.1016/j.suronc.2016.07.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Hepatoblastoma is the most common malignant liver tumor in children. On the other hand in the adult HB is very rare and characterized by unfavorable prognosis. A review of the entire literature was performed: 58 articles and 63 cases of HB were found. The patient's data were collected and analyzed. No correlation with hepatitis virus was found and AFP was elevated in most cases. Usually HB forms a large single mass in the liver and presents aggressive behavior, with local invasiveness and metastatic spread. The current median survival time is 5 months, with a 1-year survival rate near 30%. Surgical resection is the only curative treatment. However major liver resections or extensive demolitions of the adjacent organs are necessary. There are no standardized protocols in the multimodal approach to this tumor. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:339 / 347
页数:9
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