Evaluation of the VersaTREK System Compared to the Bactec MGIT 960 System for First-Line Drug Susceptibility Testing of Mycobacterium tuberculosis

被引:17
作者
Espasa, M. [1 ,2 ]
Salvado, M. [1 ,3 ]
Vicente, E. [1 ,3 ]
Tudo, G.
Alcaide, F. [6 ,9 ]
Coll, P. [4 ,5 ,7 ]
Martin-Casabona, N. [8 ]
Torra, M. [1 ,2 ]
Fontanals, D. [1 ,2 ]
Gonzalez-Martin, J.
机构
[1] Univ Autonoma Barcelona, Dept Genet & Microbiol, E-08193 Barcelona, Spain
[2] Corp Sanitaria Parc Tauli, UDIAT CD, Lab Microbiol, Sabadell, Spain
[3] Lab Referencia Catalunya, Lab Microbiol, Barcelona, Spain
[4] Univ Barcelona, Dept Anat Patol Farmacol & Microbiol, Hosp Clin Barcelona, Serv Microbiol CDB, Barcelona, Spain
[5] Univ Barcelona, Hosp Clin, Barcelona Ctr Int Hlth Res CRESIB, Barcelona, Spain
[6] Univ Barcelona, Dept Patol & Terapeut Expt, Barcelona, Spain
[7] Hosp Univ Santa Creu & Sant Pau, Serv Microbiol, Barcelona, Spain
[8] Hosp Univ Vall Hebron, Serv Microbiol, Barcelona, Spain
[9] Hosp Univ Bellvitge, Serv Microbiol, Lhospitalet De Llobregat, Spain
关键词
ANTITUBERCULOUS DRUGS; RADIOMETRIC METHOD; ESP; PYRAZINAMIDE; COMPLEX;
D O I
10.1128/JCM.06432-11
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The aim of this study was to evaluate the reliability of the VersaTREK system for Mycobacterium tuberculosis drug susceptibility testing compared with results obtained with the Bactec MGIT 960 system. A total of 67 strains were evaluated. Overall agreement was at 98.5%. Kappa indexes were 1.0 for isoniazid, rifampin, and ethambutol, 0.937 for pyrazinamide, and 0.907 for streptomycin. The VersaTREK system is validated for M. tuberculosis drug susceptibility testing.
引用
收藏
页码:488 / 491
页数:4
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