The discovery of ghrelin - A personal memory

被引：32
作者：
Kojima, Masayasu [1 ]
机构：
[1] Kurume Univ, Inst Life Sci, Fukuoka 8390864, Japan
来源：
REGULATORY PEPTIDES | 2008年 / 145卷 / 1-3期
关键词：
ghrelin; stomach; acyl-modification; octanoic acid; GHS-R;
D O I：
10.1016/j.regpep.2007.09.023
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The endogenous ligand for growth-hormone secretagogue receptor (GHS-R) was purified from the stomach and named it "ghrelin," after the word root "ghre" in Proto-Indo-European languages meaning "grow", since ghrelin has potent growth hormone (GH) releasing activity. Ghrelin plays important roles for maintaining growth hormone release and energy homeostasis in vertebrates. In this essay, I described my, personal memory on the discovery of ghrelin in the year 1999. (c) 2007 Elsevier B.V. All rights reserved.
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页码：2 / 6
页数：5
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