A multibiomarker approach in Coris julis living in a natural environment

被引：55

作者：

Fasulo, Salvatore ^{[1
]}

Marino, Sergio ^{[2
]}

Mauceri, Angela ^{[1
]}

Maisano, Maria ^{[1
]}

Giannetto, Alessia ^{[1
]}

D'Agata, Alessia ^{[1
]}

Parrino, Vincenzo ^{[1
]}

Minutoli, Roberta ^{[1
]}

De Domenico, Elena ^{[1
]}

机构：

[1] Univ Messina, Dipartimento Biol Anim & Ecologia Marina, Messina, Italy

[2] Agenzia Reg Protez Ambiente ARPA Sicilia, I-90129 Palermo, Italy

来源：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | 2010年 / 73卷 / 07期

关键词：

Biomarker; CYP1A; GST; Genotoxicity; Esterase; C; julis; NUCLEAR ABNORMALITIES; MICRONUCLEUS TEST; MARINE FISH; IN-VITRO; DNA DAMAGE; ACETYLCHOLINESTERASE; CONTAMINATION; ERYTHROCYTES; INDUCTION; BIOMARKER;

D O I：

10.1016/j.ecoenv.2010.01.008

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

To monitor the health of aquatic organisms, biomarkers have been used as effective tools in assessing environmental risk. In this study was examined the teleost Cons julis, sampled in two marine sites in Messina (Italy) at different pollution degree, Milazzo, characterized by a strong anthropogenic impact, and Marinello, the natural reserve. C. julis is a species particularly suitable to biomonitoring because its feeding habits favor bio-accumulation of xenobiotics. The following biomarkers were used to estimate the impact of highly persistent pollutants: cellular localization of cytochrome P4501A (CYP1A) and glutathione-S-transferase (CST) in the liver, their hepatic expression at the mRNA level, the enzymatic activity (EROD and BPMO), the micronucleus and comet assays in the blood, esterases (AChE in the brain and BChE in the blood) activity and evaluation of PAH metabolites in the bile. The present findings provide evidence of statistically significant differences in parameters between individuals collected in two sites. (C) 2010 Elsevier Inc. All rights reserved.

引用

页码：1565 / 1573

页数：9

共 67 条

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