Tissue and tumor mosaicism of the myotonin protein kinase gene trinucleotide repeat in a patient with multiple basal cell carcinomas associated with myotonic dystrophy

被引：15

作者：

Bañuls, J

Botella, R

Palau, F

Ramón, R

Díaz, C

Payá, A

Carnero, L

Vergara, G

机构：

[1] Hosp Gen Alicante, Serv Dermatol, Alicante 03010, Spain

[2] Hosp Gen Alicante, Dept Neurol, Alicante 03010, Spain

[3] Hosp Gen Alicante, Dept Pathol, Alicante 03010, Spain

[4] Consejo Super Invest Cient, Inst Biomed, Valencia, Spain

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2004年 / 50卷 / 02期

关键词：

D O I：

10.1016/S0190-9622(03)00125-7

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We describe the third case (to our knowledge) of multiple basal cell carcinoma associated with myotonic dystrophy and carry out a genetic study of the tumor comparing it with healthy skin. We consider that our results show that this association might be not a purely random phenomenon and that the particular genetic characteristics of this disorder might have a role in the pathogenesis of the tumor.

引用

页码：S1 / S3

页数：3

共 19 条

[1] Myotonic dystrophy and basal cell carcinoma - a true association? [J].