New method for the general synthesis of [1,2,4]triazolo[1,5-a]pyridines

被引：45
|
作者：
Huntsman, E [1 ]
Balsells, J [1 ]
机构：
[1] Merck & Co Inc, Merck Res Labs, Proc Res Dept, Rahway, NJ 07065 USA
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 2005卷 / 17期
关键词：
nitrogen heterocycles; fused ring systems; cyclization;
D O I：
10.1002/ejoc.200500247
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[1,2,4]Triazolo[1,5-a]pyridines without substituents on the 2-position have been prepared from 2-aminopyridines by cyclization of N-(pyrid-2-yl)formamidoximes with trifluoroacetic anhydride. Triazoles substituted at any position on the pyridine ring may be prepared in good yields and under mild reaction conditions. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005).
引用
收藏
页码：3761 / 3765
页数：5
相关论文
共 50 条
  • [1] New synthesis for 1,2,4-triazolo[1,5-a]pyridines and new 1,2,4-triazolo[1,5-a]isoquinolines
    Hussein, AM
    Sherif, SM
    Atalla, AA
    POLISH JOURNAL OF CHEMISTRY, 1996, 70 (07) : 872 - 879
  • [2] A new synthesis for 1,2,4-triazolo[1,5-a]-pyridines and 1,2,4-triazolo[1,5-a]isoquinolines
    Hussein, AM
    Sherif, SM
    Atalla, AA
    MONATSHEFTE FUR CHEMIE, 1996, 127 (11): : 1153 - 1160
  • [3] Methods of synthesis of [1,2,4]triazolo[1,5-a]pyridines (microreview)
    Vorob'ev, Aleksey Yu
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2019, 55 (08) : 695 - 697
  • [4] New approach toward the synthesis of deuterated pyrazolo[1,5-a] pyridines and 1,2,4-triazolo[1,5-a] pyridines
    Vorob'ev, Aleksey Yu.
    Supranovich, Vyacheslav I.
    Borodkin, Gennady I.
    Shubin, Vyacheslav G.
    BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2017, 13 : 800 - 805
  • [5] One step efficient synthesis of [1,2,4]triazolo[1,5-a]pyridines
    Ismail, AE
    AFINIDAD, 1996, 53 (466) : 410 - 412
  • [6] Efficient one step synthesis of [1,2,4]triazolo[1,5-a]-pyridines
    Ismail, AEH
    PHARMAZIE, 1996, 51 (12): : 982 - 983
  • [7] A NEW METHOD FOR THE SYNTHESIS OF [1,2,4]TRIAZOLO[1,5-a]PYRIDINE DERIVATIVES
    Zhao, Wei-Ming
    Ge, Yan-Qing
    Xu, Wei-Ren
    Zhao, Gui-Long
    Jia, Jiong
    Wang, Jian-Wu
    HETEROCYCLES, 2013, 87 (04) : 869 - +
  • [8] Utility of cyano acid hydrazide in heterocyclic chemistry: A new route for the synthesis of new 1,2,4-triazolo[1,5-a]pyridines and 1,2,4-triazolo[1,5-a]isoquinolines
    Haleem, A
    Hussein, M
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 1998, 53 (04): : 488 - 494
  • [9] Utility of cyano acid hydrazide in heterocyclic chemistry: A new route for the synthesis of new 1,2,4-triazolo[1,5-a]pyridines and 1,2,4-triazolo[1,5-a]isoquinolines
    Hussein, Abdel Haleem Mostafa
    Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1998, 53 (04): : 488 - 494
  • [10] SYNTHESIS AND CRYSTAL-STRUCTURE OF PIPERIDINIUM 2-ARYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINIDES AND THEIR NEUTRALIZATION TO 2-ARYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINES
    HADI, A
    MARTIN, N
    SEOANE, C
    SOTO, JL
    ALBERT, A
    CANO, F
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1992, 29 (05) : 1229 - 1235
12345