A wireless endoscopy capsule suitable for imaging of the equine stomach and small intestine

被引:7
作者
Steinmann, Mei [1 ]
Bezugley, Rebecca J. [2 ]
Bond, Stephanie L. [1 ]
Pomrantz, Jill S. [3 ]
Leguillette, Renaud [1 ,2 ]
机构
[1] Univ Calgary, Fac Vet Med, Dept Vet Clin & Diagnost Serv, Calgary, AB T2N 4N1, Canada
[2] Moore Equine Vet Ctr, Rocky View Cty, AB, Canada
[3] Infiniti Med LLC, Menlo Pk, CA USA
关键词
capsule endoscopy; endoscopy; gastroscopy; GASTROINTESTINAL MOTILITY; TRANSIT-TIME; HORSES; ENTEROSCOPY; ILEUS;
D O I
10.1111/jvim.15825
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Background Capsule endoscopy offers a new method for visualization of the gastrointestinal mucosa in horses where other imaging technologies have diagnostic limitations. Objectives To (1) test the feasibility of using this novel endoscopy capsule to visualize intestinal mucosa in horses, including an objective assessment of image quality, (2) assess how changes in preadministration preparation affect the transit time and the amount of gastrointestinal mucosa visualized, and (3) describe intestinal mucosa lesions in healthy horses. Animals Five healthy adult horses. Methods Three protocols were used in a crossover study design. Protocols varied in time fasted, amount of oral fluid administered, and exercise. Manure was radiographically inspected for capsule recovery. Percentage of visible gastrointestinal mucosa was objectively assessed. Results Detailed images of the gastrointestinal mucosa were recorded with all 3 protocols, including images of the pylorus, major duodenal papilla, individual villi, and ileocecal junction. Visualization of large intestinal mucosa was poor. Interobserver agreement on image quality was excellent. Capsule administration after feed withholding for 24 hours provided the greatest percentage of visible mucosa in the stomach and small intestine. Total transit time to capsule excretion was 6.5 (3-8.75) days. Of 15 capsules administered, 3 were not recovered. Lesions visualized included mucosal erosion, ulceration and hemorrhage, areas of thickened mucosa, and evidence of parasitism. Conclusions This novel endoscopic capsule appears safe, practical, and noninvasive in horses; however, variability in capsule excretion time must be taken into account for clinical application.
引用
收藏
页码:1622 / 1630
页数:9
相关论文
共 25 条
[1]   A randomized trial comparing wireless capsule endoscopy with push enteroscopy for the detection of small-bowel lesions [J].
Appleyard, M ;
Fireman, Z ;
Glukhovsky, A ;
Jacob, H ;
Shreiver, R ;
Kadirkamanathan, S ;
Lavy, A ;
Lewkowicz, S ;
Scapa, E ;
Shofti, R ;
Swain, P ;
Zaretsky, A .
GASTROENTEROLOGY, 2000, 119 (06) :1431-1438
[2]  
장화석, 2008, [PROGRESS in MEDICAL PHYSICS, 의학물리], V19, P125
[3]   Evaluation of capsule endoscopy to detect mucosal lesions associated with gastrointestinal bleeding in dogs [J].
Davignon, D. L. ;
Lee, A. C. Y. ;
Johnston, A. N. ;
Bowman, D. D. ;
Simpson, K. W. .
JOURNAL OF SMALL ANIMAL PRACTICE, 2016, 57 (03) :148-158
[4]  
Delesalle C, 2006, VLAAMS DIERGEN TIJDS, V75, P122
[5]   The effect of sedation on gastric emptying of a liquid marker in ponies [J].
Doherty, TJ ;
Andrews, FM ;
Provenza, MK ;
Frazier, DL .
VETERINARY SURGERY, 1999, 28 (05) :375-379
[6]  
Gibbard D., 2015, THESIS
[7]   Wireless capsule endoscopy [J].
Iddan, G ;
Meron, G ;
Glukhovsky, A ;
Swain, P .
NATURE, 2000, 405 (6785) :417-417
[8]  
Koenig J, 2006, CAN VET J, V47, P551
[9]   Clinical features and management of equine post operative ileus: Survey of diplomates of the European Colleges of Equine Internal Medicine (ECEIM) and Veterinary Surgeons (ECVS) [J].
Lefebvre, D. ;
Pirie, R. S. ;
Handel, I. G. ;
Tremaine, W. H. ;
Hudson, N. P. H. .
EQUINE VETERINARY JOURNAL, 2016, 48 (02) :182-187
[10]   Gastric emptying of oral rehydration solutions at rest and after exercise in horses [J].
Leon, LAS ;
Hodgson, DR ;
Rose, RJ .
RESEARCH IN VETERINARY SCIENCE, 1997, 63 (02) :183-187