Importance of drug resistance in gonococci: from mechanisms to monitoring

被引：14

作者：

Dillon, JAR ^{[1
]}

Pagotto, F ^{[1
]}

机构：

[1] Univ Ottawa, Dept Biochem Microbiol & Immunol, Ottawa, ON, Canada

来源：

CURRENT OPINION IN INFECTIOUS DISEASES | 1999年 / 12卷 / 01期

关键词：

D O I：

10.1097/00001432-199902000-00007

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Neisseria gonorrhoeae isolates continue to develop an impressive arsenal of resistance mechanisms to antimicrobial agents, including resistance to some of the antibiotics presently recommended for the treatment of gonococcal infections. The need for antimicrobial susceptibility monitoring in gonococcal isolates and new, effective, antigonococcal treatments has never been greater. Curr Opin Infect Dis 12:35-40. (C) 1999 Lippincott Williams & Wilkins.

引用

页码：35 / 40

页数：6

共 53 条

[1] Increasing prevalence of penicillinase-producing Neisseria gonorrhoeae and the emergence of high-level, plasmid-mediated tetracycline resistance among gonococcal isolates in The Gambia [J].

Adegbola, RA ;

Sabally, S ;

Corrah, T ;

West, B ;

Mabey, D .

TROPICAL MEDICINE & INTERNATIONAL HEALTH, 1997, 2 (05) :428-432

[2] 2 HIGHLY SIMILAR MULTIDRUG TRANSPORTERS OF BACILLUS-SUBTILIS WHOSE EXPRESSION IS DIFFERENTIALLY REGULATED [J].

AHMED, M ;

LYASS, L ;

MARKHAM, PN ;

TAYLOR, SS ;

VAZQUEZLASLOP, N ;

NEYFAKH, AA .

JOURNAL OF BACTERIOLOGY, 1995, 177 (14) :3904-3910

[3] NEISSERIA-GONORRHOEAE ACQUIRES MUTATIONS IN ANALOGOUS REGIONS OF GYRA AND PARC IN FLUOROQUINOLONE-RESISTANT ISOLATES [J].

BELLAND, RJ ;

MORRISON, SG ;

ISON, C ;

HUANG, WM .

MOLECULAR MICROBIOLOGY, 1994, 14 (02) :371-380

[4] ACTIVITIES OF 3 INVESTIGATIONAL FLUOROQUINOLONES (BAY-Y-3118, DU-6859A, AND CLINAFLOXACIN) AGAINST NEISSERIA-GONORRHOEAE ISOLATES WITH DIMINISHED SUSCEPTIBILITIES TO CIPROFLOXACIN AND OFLOXACIN [J].

CARLYN, CJ ;

DOYLE, LJ ;

KNAPP, CC ;

LUDWIG, MD ;

WASHINGTON, JA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (07) :1606-1608

[5] Plasmid analysis of Neisseria gonorrhoeae isolates and dissemination of tetM genes in southern Africa 1993-1995 [J].

Chalkley, LJ ;

van Rensburg, MNJ ;

Matthee, PC ;

Ison, CA ;

Botha, PL .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 40 (06) :817-822

[6] Do spermicides containing nonoxynol-9 prevent sexually transmitted infections?: A meta-analysis [J].

Cook, RL ;

Rosenberg, MJ .

SEXUALLY TRANSMITTED DISEASES, 1998, 25 (03) :144-150

[7] REDUCED UPTAKE OF CIPROFLOXACIN IN A RESISTANT STRAIN OF NEISSERIA-GONORRHOEAE AND TRANSFORMATION OF RESISTANCE TO OTHER STRAINS [J].

CORKILL, JE ;

PERCIVAL, A ;

LIND, M .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1991, 28 (04) :601-604

[8] In-vitro antimicrobial activity of HSR-903, a new fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae with quinolone resistance-associated alterations in GyrA and ParC [J].

Deguchi, T ;

Yasuda, M ;

Ishihara, S ;

Takahashi, Y ;

Okezaki, E ;

Nagata, O ;

Saito, I ;

Kawada, Y .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 40 (03) :437-439

[9] Fluoroquinolone treatment failure in gonorrhea - Emergence of a Neisseria gonorrhoeae strain with enhanced resistance to fluoroquinolones [J].

Deguchi, T ;

Saito, I ;

Tanaka, M ;

Sato, K ;

Deguchi, K ;

Yasuda, M ;

Nakano, M ;

Nishino, Y ;

Kanematsu, E ;

Ozeki, S ;

Kawada, Y .

SEXUALLY TRANSMITTED DISEASES, 1997, 24 (05) :247-250

[10] Involvement of the gonococcal MtrE protein in the resistance of Neisseria gonorrhoeae to toxic hydrophobic agents [J].

Delahay, RM ;

Robertson, BD ;

Balthazar, JT ;

Shafer, WM ;

Ison, CA .

MICROBIOLOGY-SGM, 1997, 143 :2127-2133

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