Geometry of tricyclic quinolizidine-piperidine alkaloids in solution by NMR spectroscopy

被引：11

作者：

Brukwicki, T ^{[1
]}

Wysocka, W ^{[1
]}

机构：

[1] Adam Mickiewicz Univ, Fac Chem, PL-60780 Poznan, Poland

来源：

JOURNAL OF MOLECULAR STRUCTURE | 1999年 / 474卷

关键词：

tricyclic quinolizidine-piperidine alkaloids; NMR spectroscopy;

D O I：

10.1016/S0022-2860(98)00574-2

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The Haasnoot equation was used to determine HCCH spectroscopy dihedral angles from H-1 NMR spectroscopy in tricyclic quinolizidine-piperidine alkaloids in solution: seco(11,12)- 12,13-didehydromultiflorine (1), seco(11,13-)- 5,6-didehydromultiflorine (2) and angustifoline (3). Ring C in the three alkaloids has quite a regular chair conformation. Ring B is a flattened chair in 1 and 3 and a sofa in 2. The geometry of 2 is similar to that of cytisine (4). (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：215 / 222

页数：8

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