Synthesis, Characterization and in vitro Antimicrobial Activity of Co(II), Cu(II), Zn(II), Cd(II) and Sn(II) Ions with {[5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl]thio}acetic Acid

In present studies, five metal complexes derivative of {[5-(4-bromophenyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid, HI, with the metal ions [Co(II), Cu(ll), Zn(II), Cd(II) and Sn(II)] have been successfully prepared in alcoholic medium. The complexes obtained are characterized quantitatively and qualitatively by using FTIR spectroscopy, electronic spectroscopy, mass spectroscopy (1)H and (13)C NMR, magnetic susceptibility and conductivity measurements. From the spectral study, all the complexes obtained as a monomeric structure and the metals centre moieties are four-coordinated and exhibited tetrahedral geometry except Cu(II) complex (square planar). Preliminary in vitro antimicrobial study indicated that all the compounds showed significant activity against the tested bacterial strains.