Adducts of Diketene, Alcohols, and Aldehydes: Useful Building Blocks for 3,4-Dihydropyrimidinones and 1,4-Dihydropyridines

被引：16

作者：

Alizadeh, Abdolali ^{[1
]}

Rostamnia, Sadegh ^{[1
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

SYNTHESIS-STUTTGART | 2010年 / 23期

关键词：

dihydropyridines; dihydropyrimidines; diketene; multicomponent reaction; neat condition; ONE-POT SYNTHESIS; SOLVENT-FREE CONDITIONS; BIGINELLI REACTION; IMPROVED PROTOCOL; CONDENSATION REACTION; 3-COMPONENT REACTION; CHANNEL ANTAGONISTS; EFFICIENT SYNTHESIS; ROOM-TEMPERATURE; DERIVATIVES;

D O I：

10.1055/s-0030-1258291

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel, one-pot, solvent-free synthesis of 3,4-dihydropyrimidin-2-(1H)-one and 1,4-dihydropyridines derivatives via a four-component cyclocondensation reaction of diketene, alcohol, and aldehyde with urea or ammonium acetate is presented.

引用

页码：4057 / 4060

页数：4