Adducts of Diketene, Alcohols, and Aldehydes: Useful Building Blocks for 3,4-Dihydropyrimidinones and 1,4-Dihydropyridines

被引：16
作者：
Alizadeh, Abdolali [1 ]
Rostamnia, Sadegh [1 ]
机构：
[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran
来源：
SYNTHESIS-STUTTGART | 2010年 / 23期
关键词：
dihydropyridines; dihydropyrimidines; diketene; multicomponent reaction; neat condition; ONE-POT SYNTHESIS; SOLVENT-FREE CONDITIONS; BIGINELLI REACTION; IMPROVED PROTOCOL; CONDENSATION REACTION; 3-COMPONENT REACTION; CHANNEL ANTAGONISTS; EFFICIENT SYNTHESIS; ROOM-TEMPERATURE; DERIVATIVES;
D O I：
10.1055/s-0030-1258291
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel, one-pot, solvent-free synthesis of 3,4-dihydropyrimidin-2-(1H)-one and 1,4-dihydropyridines derivatives via a four-component cyclocondensation reaction of diketene, alcohol, and aldehyde with urea or ammonium acetate is presented.
引用
收藏
页码：4057 / 4060
页数：4
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