The zebrafish as a model system in developmental, toxicological and transgenic research

被引:157
作者
Lele, Z
Krone, PH
机构
[1] Department of Anatomy and Cell Biology, University of Saskatchewan, Health Services Building, Saskatoon, Sask. S7N 5E5
关键词
zebrafish; developmental biology; transgenic fish; toxicology;
D O I
10.1016/0734-9750(96)00004-3
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The zebrafish has long been used as a model system in fisheries biology and toxicology. More recently, it has also become the focus of a major research effort into understanding the molecular and cellular events which dictate the development of vertebrate embryos. As well, the zebrafish has proven attractive in studies examining the factors which affect the creation of transgenic fish and the expression of transgenes. The advances which have been made in these areas have firmly established this small aquarium fish as a major model system in biological and biotechnological research.
引用
收藏
页码:57 / 72
页数:16
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