Biology of COVID-19 and related viruses: Epidemiology, signs, symptoms, diagnosis, and treatment

被引:11
作者
Kaye, Alan D. [1 ]
Cornett, Elyse M. [2 ]
Brondeel, Kimberley C. [3 ]
Lerner, Zachary I. [4 ]
Knight, Haley E. [5 ]
Erwin, Abigail [4 ,5 ]
Charipova, Karina [6 ]
Gress, Kyle L.
Urits, Ivan [7 ]
Urman, Richard D. [8 ]
Fox, Charles J. [2 ]
Kevil, Christopher G. [1 ]
机构
[1] LSU Hlth Shreveport, 1501 Kings Highway, Shreveport, LA 71103 USA
[2] LSU Hlth Shreveport, Dept Anesthesiol, 1501 Kings Highway, Shreveport, LA 71103 USA
[3] Univ Texas Med Branch, 301 Univ Blvd, Galveston, TX 77555 USA
[4] LSU Hlth Sci Ctr New Orleans, 1901 Perdido St, New Orleans, LA 70112 USA
[5] Louisiana State Univ, Hlth Sci Ctr, New Orleans, LA 70112 USA
[6] Georgetown Univ, Sch Med, Washington, DC 20007 USA
[7] Harvard Med Sch, Dept Anesthesiol Crit Care & Pain Med, Beth Israel Deaconess Med Ctr, Boston, MA USA
[8] Harvard Med Sch, Brigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
关键词
COVID-19; coronavirus; outbreak; upper-respiratory tract illnesses; respiratory droplets; CORONAVIRUS;
D O I
10.1016/j.bpa.2020.12.003
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Coronaviruses belong to the family Coronaviridae order Nidovirales and are known causes of respiratory and intestinal disease in various mammalian and avian species. Species of coronaviruses known to infect humans are referred to as human coronaviruses (HCoVs). While traditionally, HCoVs have been a significant cause of the common cold, more recently, emergent viruses, including severe acute respiratory syndrome coronavirus (SARS-CoV-2) has caused a global pandemic. Here, we discuss coronavirus disease (COVID-19) biology, pathology, epidemiology, signs and symptoms, diagnosis, treatment, and recent clinical trials involving promising treatments. (c) 2020 Elsevier Ltd. All rights reserved.
引用
收藏
页码:269 / 292
页数:24
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