A novel sensing platform based on periodate-oxidized chitosan

被引：13

作者：

Feng, Yan ^{[1
]}

Yang, Limin ^{[1
]}

Li, Feng ^{[1
]}

机构：

[1] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Shandong Prov Key Lab Biochem Anal, Qingdao 266042, Peoples R China

来源：

ANALYTICAL METHODS | 2010年 / 2卷 / 12期

基金：

中国国家自然科学基金;

关键词：

GLASSY-CARBON ELECTRODE; ELECTROCATALYTIC REDUCTION; COVALENT IMMOBILIZATION; SIMPLE STRATEGY; THIONINE; CHROMIUM(VI); SURFACE; FILM;

D O I：

10.1039/c0ay00499e

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel thionine (TH) sensing platform was proposed based on immobilization of TH on a periodate-oxidized chitosan (CS) modified glassy carbon electrode (GCE) surface. Oxidation of CS by periodate can lead to the cleavage of carbon-carbon bonds on the pyranosidic ring of CS, with the generation of dialdehyde groups. TH, an electroactive mediator, was selected as a model of amine compounds to react with the aldehyde group via Schiff-base reaction. Due to the resulting aldehyde-enriched surface and covalent immobilization of TH on periodate-oxidized CS, the CS-grafted-TH showed a pronounced electrochemical response with high stability. The application of the fabricated TH sensing platform as a hydrogen peroxide (H2O2) sensor was also investigated and it exhibited a rapid response to H2O2 within 4 s. The linear calibration ranged from 1.0 x 10(-5) to 1.83 x 10(-3) M with a detection limit of 4.0 x 10(-6) M.

引用

页码：2011 / 2016

页数：6

共 37 条

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