Form, Function, and Regulation of ARGONAUTE Proteins

被引:290
作者
Mallory, Allison [1 ]
Vaucheret, Herve [1 ]
机构
[1] INRA, Inst Jean Pierre Bourgin, UMR 1318, F-78026 Versailles, France
基金
欧盟地平线“2020”;
关键词
DIRECTED DNA METHYLATION; SMALL RNA DUPLEXES; SIRNA BIOGENESIS; SILENCING SUPPRESSOR; MICRORNA TARGETS; MESSENGER-RNA; ARABIDOPSIS ARGONAUTE1; LEAF DEVELOPMENT; MIRNA PATHWAY; HUMAN-CELLS;
D O I
10.1105/tpc.110.080671
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Both transcriptional (TGS) and posttranscriptional gene silencing (PTGS) are conserved eukaryotic gene regulatory mechanisms, integral for taming exogenous (viruses and bacteria) or endogenous (repetitive elements and transposons) invasive nucleic acids to minimize their impact on genome integrity and function. TGS and PTGS also are essential for controlling the expression of protein coding genes throughout development or in response to environmental stimuli. In plants and animals, at least one member of the conserved ARGONAUTE (AGO) protein family comprises the catalytic engine of the silencing complex, which is guided by sequence-specific small RNA to cognate RNA. In this review, we present general features of plant and animal AGO proteins and detail our knowledge on the 10 Arabidopsis thaliana AGOs.
引用
收藏
页码:3879 / 3889
页数:11
相关论文
共 91 条
[1]  
Allen E, 2005, CELL, V121, P207, DOI 10.1016/j.cell.2005.04.004
[2]   A two-hit trigger for siRNA biogenesis in plants [J].
Axtell, Michael J. ;
Jan, Calvin ;
Rajagopalan, Ramya ;
Bartel, David P. .
CELL, 2006, 127 (03) :565-577
[3]   Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein [J].
Azevedo, Jacinthe ;
Garcia, Damien ;
Pontier, Dominique ;
Ohnesorge, Stephanie ;
Yu, Agnes ;
Garcia, Shahinez ;
Braun, Laurence ;
Bergdoll, Marc ;
Hakimi, Mohamed Ali ;
Lagrange, Thierry ;
Voinnet, Olivier .
GENES & DEVELOPMENT, 2010, 24 (09) :904-915
[4]   MicroRNAs: Target Recognition and Regulatory Functions [J].
Bartel, David P. .
CELL, 2009, 136 (02) :215-233
[5]   Arabidopsis ARGONAUTE1 is an RNA Slicer that selectively recruits rnicroRNAs and short interfering RNAs [J].
Baumberger, N ;
Baulcombe, DC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (33) :11928-11933
[6]   The polerovirus silencing suppressor PO targets ARGONAUTE proteins for degradation [J].
Baumberger, Nicolas ;
Tsai, Ching-Hsui ;
Lie, Miranda ;
Havecker, Ericka ;
Baulcombe, David C. .
CURRENT BIOLOGY, 2007, 17 (18) :1609-1614
[7]   Relief of microRNA-mediated translational repression in human cells subjected to stress [J].
Bhattacharyya, Suvendra N. ;
Habermacher, Regula ;
Martine, Ursula ;
Closs, Ellen I. ;
Filipowicz, Witold .
CELL, 2006, 125 (06) :1111-1124
[8]   AGO1 defines a novel locus of Arabidopsis controlling leaf development [J].
Bohmert, K ;
Camus, I ;
Bellini, C ;
Bouchez, D ;
Caboche, M ;
Benning, C .
EMBO JOURNAL, 1998, 17 (01) :170-180
[9]   The polerovirus F box protein PO targets ARGONAUTE1 to suppress RNA silencing [J].
Bortolamiol, Diane ;
Pazhouhandeh, Maghsoud ;
Marrocco, Katia ;
Genschik, Pascal ;
Ziegler-Graff, Veronique .
CURRENT BIOLOGY, 2007, 17 (18) :1615-1621
[10]   Widespread translational inhibition by plant miRNAs and siRNAs [J].
Brodersen, Peter ;
Sakvarelidze-Achard, Lali ;
Bruun-Rasmussen, Marianne ;
Dunoyer, Patrice ;
Yamamoto, Yoshiharu Y. ;
Sieburth, Leslie ;
Voinnet, Olivier .
SCIENCE, 2008, 320 (5880) :1185-1190