Relationship between sulfaguanidine resistance and increased cellulose production in Acetobacter xylinum BPR3001E

被引：6

作者：

Ishikawa, A ^{[1
]}

Tsuchida, T ^{[1
]}

Yoshinaga, F ^{[1
]}

机构：

[1] Biopolymer Res Co Ltd, KSP R&D B 1015, Kawasaki, Kanagawa 2130012, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1998年 / 62卷 / 06期

关键词：

cellulose; sulfaguanidine; p-aminobenzoic acid; ATP;

D O I：

10.1271/bbb.62.1234

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mechanism of the increased cell growth and cellulose production of Acetobacter xylinum subsp. sucrofermentans BPR3001E, a sulfaguanidine (SG)-resistant mutant, was investigated, We found that adding p-aminobenzoic acid (PABA) to cultures of the parent strain, BPR2001, led to increased levels of intracellular adenosine-related purine compounds and increased cellulose production. Furthermore, adding ATP increased the. cellulose production by permeabilized BPR2001 cells. On the other hand, the intracellular levels of PABA and adenosine-related purine compounds in BPR3001E cells mere higher than those in BPR2001 cells, These results suggest that SG resistance increases enhance cellulose production through increased levels of intracellular high-energy compounds caused by increased PABA biosynthesis, reflecting the promoted supply of cellulose precursors.

引用

页码：1234 / 1236

页数：3

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