Polyelectrolyte nanoparticles based on functionalized silica and pillar[5]arene derivatives for recognition of model proteins

被引:0
作者
Ziatdinova, R. V. [1 ]
Nazarova, A. A. [1 ]
Yakimova, L. S. [1 ]
Mostovaya, O. A. [1 ]
Kalinin, V. I. [1 ]
Osin, Y. N. [2 ]
Stoikov, I. I. [1 ]
机构
[1] Kazan Volga Reg Fed Univ, AM Butlerov Chem Inst, 18 Ul Kremlevskaya, Kazan 420008, Russia
[2] Kazan Volga Reg Fed Univ, Interdisciplinary Ctr Analyt Microscopy, 18 Ul Kremlevskaya, Kazan 420008, Russia
基金
俄罗斯科学基金会;
关键词
silica; surface modification; pillar[5]arene; self-assembly; proteins; bovine serum albumin; lysozyme; BOVINE SERUM-ALBUMIN; SELECTIVE ADSORPTION; SEPARATION; PARTICLES; LYSOZYME; DELIVERY; SUBSTITUENTS; MEMBRANE;
D O I
10.1007/s11172-019-2667-0
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The paper reports the first synthesis of positively charged hybrid organic-inorganic silicon dioxide nanoparticles with an average particle diameter of 28 nm modified with 1-[3-(diethylamino)propyl]-3-[3-(triethoxysilyl)propyl] urea and pillar[5]arene derivatives containing negatively charged groups, which form nanoparticles with an average diameter of 40 nm in an aqueous solution. These nanoparticles were utilized in a new procedure developed for the preparation of mixed polyelectrolyte particles. Spectroscopic studies (UV spectroscopy, dynamic light scattering) showed that the resulting compounds are able to recognize biopolymers, proteins (bovine serum albumin and lysozyme).
引用
收藏
页码:2065 / 2074
页数:10
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