The Beneficial Effects of Quercetin, Curcumin, and Resveratrol in Obesity

被引:152
作者
Zhao, Yueshui [1 ]
Chen, Bo [2 ]
Shen, Jing [1 ]
Wan, Lin [3 ]
Zhu, Yinxin [4 ]
Yi, Tao [5 ]
Xiao, Zhangang [1 ,6 ]
机构
[1] Southwest Med Univ, Sch Pharm, Dept Pharmacol, Lab Mol Pharmacol, Luzhou, Sichuan, Peoples R China
[2] Kunming Med Univ, Expt Ctr Med Sci Res, Kunming, Yunnan, Peoples R China
[3] Childrens Hosp Soochow, Dept Hematol & Oncol, Suzhou, Jiangsu, Peoples R China
[4] Soochow Univ, Affiliated Hosp 3, Dept Gastroenterol, Changzhou, Jiangsu, Peoples R China
[5] Hong Kong Baptist Univ, Sch Chinese Med, Kowloon, Hong Kong, Peoples R China
[6] Southwest Med Univ, Sch Pharm, Minist Educ, Key Lab Med Electrophysiol, Luzhou, Sichuan, Peoples R China
基金
中国国家自然科学基金;
关键词
BROWN ADIPOSE-TISSUE; ACTIVATED RECEPTOR-GAMMA; ONION PEEL EXTRACT; HIGH-FAT; OXIDATIVE STRESS; METABOLIC SYNDROME; ENERGY-EXPENDITURE; LIPOPROTEIN-LIPASE; GENE-EXPRESSION; COLD-EXPOSURE;
D O I
10.1155/2017/1459497
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Over the past two decades, obesity has been one of the major public health concerns in most countries. In the search for new molecules that could be used for the treatment of obesity, good perspectives have been opened up for polyphenols, a class of natural bioactive phytochemicals. Experimental and limited clinical trial evidence supports that some polyphenols such as quercetin, curcumin, and resveratrol have potential benefit functions on obesity treatment. This brief review focuses on the main functions of the above-named polyphenols on adipose tissue. These polyphenols may play beneficial effects on adipose tissue under obese condition by alleviating intracellular oxidative stress, reducing chronic low-grade inflammation, inhibiting adipogenesis and lipogenesis, and suppressing the differentiation of preadipocytes to mature adipocytes.
引用
收藏
页数:8
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