(E)-1-(4-Aminophenyl)-3-(naphthalen-2-yl)prop-2-en-1-one

被引:2
作者
Kobkeatthawin, Thawanrat [1 ]
Chantrapromma, Suchada [1 ]
Saewan, Nisakorn [2 ]
Fun, Hoong-Kun [3 ]
机构
[1] Prince Songkla Univ, Fac Sci, Dept Chem, Crystal Mat Res Unit, Hat Yai 90112, Songkhla, Thailand
[2] Mae Fah Luang Univ, Sch Cosmet Sci, Muang 57100, Chiang Rai, Thailand
[3] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, George Town 11800, Malaysia
来源
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷
关键词
X-RAY; DIFFRACTION; CHALCONES; AGENTS; PROBE;
D O I
10.1107/S1600536811014024
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The molecule of the title chalcone derivative, C19H15NO, exists in a trans configuration with respect to the C=C double bond. The molecule is slightly twisted with a dihedral angle of 6.12 (12)degrees between the benzene ring and the naphthalene ring system. The prop-2-en-1-one bridge is nearly planar, with an r.m.s. deviation of 0.0194 (2), and makes dihedral angles of 8.05 (19) and 11.47 (18)degrees with the benzene ring and the naphthalene ring system, respectively. In the crystal, molecules are linked by N-H center dot center dot center dot O hydrogen bonds into chains along the b axis. Weak N-H center dot center dot center dot pi and C-H center dot center dot center dot pi interactions and a short N center dot center dot center dot O contact [2.974 (4) angstrom] are also observed.
引用
收藏
页码:O1204 / U1141
页数:11
相关论文
共 16 条
[1]   TABLES OF BOND LENGTHS DETERMINED BY X-RAY AND NEUTRON-DIFFRACTION .1. BOND LENGTHS IN ORGANIC-COMPOUNDS [J].
ALLEN, FH ;
KENNARD, O ;
WATSON, DG ;
BRAMMER, L ;
ORPEN, AG ;
TAYLOR, R .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1987, (12) :S1-S19
[2]  
[Anonymous], 2009, APEX2 SAINT SADABS
[3]   Synthesis and biological screening of a combinatorial library of β-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents [J].
Bandgar, Babasaheb P. ;
Gawande, Shrikant S. .
BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 18 (05) :2060-2065
[4]   Synthesis and cytotoxic, anti-inflammatory, and anti-oxidant activities of 2′,5′-dialkoxylchalcones as cancer chemopreventive agents [J].
Cheng, Jen-Hao ;
Hung, Chi-Feng ;
Yang, Shyh-Chyun ;
Wang, Jih-Pyang ;
Won, Shen-Jeu ;
Lin, Chun-Nan .
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (15) :7270-7276
[5]   A NITROGEN-GAS-STREAM CRYOSTAT FOR GENERAL X-RAY-DIFFRACTION STUDIES [J].
COSIER, J ;
GLAZER, AM .
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1986, 19 (02) :105-107
[6]   1-(4-bromophenyl)-3-(4-ethoxyphenyl)prop-2-en-1-one [J].
Fun, Hoong-Kun ;
Patil, P. S. ;
Dharmaprakash, S. M. ;
Chantrapromma, Suchada .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 :O1540-U2729
[7]   Photophysical properties, laser activity and photoreactivity of a heteroaryl chalcone - A model of solvatochromic fluorophore [J].
Gaber, M. ;
Ei-Daly, S. A. ;
Fayed, T. A. ;
Ei-Sayed, Y. S. .
OPTICS AND LASER TECHNOLOGY, 2008, 40 (03) :528-537
[8]   (E)-3-(4-Ethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one [J].
Horkaew, Jirapa ;
Chantrapromma, Suchada ;
Saewan, Nisakorn ;
Fun, Hoong-Kun .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 :O2346-U638
[9]   Chalcones as potent tyrosinase inhibitors: the effect of hydroxyl positions and numbers [J].
Nerya, O ;
Musa, R ;
Khatib, S ;
Tamir, S ;
Vaya, J .
PHYTOCHEMISTRY, 2004, 65 (10) :1389-1395
[10]   Synthesis, physicochemical properties and antimicrobial evaluation of new (E)-chalcones [J].
Nowakowska, Z. ;
Kedzia, B. ;
Schroeder, G. .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (04) :707-713