Langerhans cell histiocytosis: old disease new treatment

被引：30

作者：

Ng-Cheng-Hin, B. ^{[1
]}

O'Hanlon-Brown, C. ^{[1
]}

Alifrangis, C. ^{[1
]}

Waxman, J. ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Dept Surg & Canc, Div Canc,Garry Weston Ctr, London W12 0NN, England

来源：

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE | 2011年 / 104卷 / 02期

关键词：

PULMONARY EOSINOPHILIC GRANULOMA; RANDOMIZED TRIAL; NERVOUS-SYSTEM; FOLLOW-UP; ADULT; THERAPY; 2-CHLORODEOXYADENOSINE; LUNG; SKIN; CHILDREN;

D O I：

10.1093/qjmed/hcq206

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Langerhans cell histiocytosis (LCH) has been previously thought of as a rare illness, but is now increasingly diagnosed as a result of the more intensive investigations of patients with cystic pulmonary disease. In recent years, treatments developed from our new understanding of the molecular biology of malignant disease have been applied to patients with LCH, and responses seen. In this review, we describe the origins, presentation and modern treatment of LCH, showing that there is new hope for patients with this condition.

引用

页码：89 / 96

页数：8