Ocular motor abnormalities in neurodegenerative disorders

被引:51
作者
Antoniades, C. A. [1 ]
Kennard, C. [1 ]
机构
[1] Univ Oxford, Nuffield Dept Clin Neurosci, Oxford OX3 9DU, England
关键词
SACCADIC EYE-MOVEMENT; FRONTOTEMPORAL LOBAR DEGENERATION; SUBTHALAMIC NUCLEUS STIMULATION; PROGRESSIVE SUPRANUCLEAR PALSY; MILD COGNITIVE IMPAIRMENT; HUNTINGTON DISEASE GENE; MEMORY-GUIDED SACCADES; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; CORTICOBASAL DEGENERATION;
D O I
10.1038/eye.2014.276
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Eye movements are a source of valuable information to both clinicians and scientists as abnormalities of them frequently act as clues to the localization of a disease process. Classically, they are divided into two main types: those that hold the gaze, keeping images steady on the retina (vestibulo-ocular and optokinetic reflexes) and those that shift gaze and redirect the line of sight to a new object of interest (saccades, vergence, and smooth pursuit). Here we will review some of the major ocular motor abnormalities present in neurodegenerative disorders.
引用
收藏
页码:200 / 207
页数:8
相关论文
共 99 条
  • [81] IMPAIRMENT OF SPATIALLY DIRECTED ATTENTION IN PATIENTS WITH PROBABLE ALZHEIMERS-DISEASE AS MEASURED BY EYE-MOVEMENTS
    SCINTO, LFM
    DAFFNER, KR
    CASTRO, L
    WEINTRAUB, S
    VAVRIK, M
    MESULAM, MM
    [J]. ARCHIVES OF NEUROLOGY, 1994, 51 (07) : 682 - 688
  • [82] Are frontotemporal lobar degeneration, progressive supranuclear palsy and corticobasal degeneration distinct diseases?
    Sha, ron Sha
    Hou, Craig
    Viskontas, Indre V.
    Miller, Bruce L.
    [J]. NATURE CLINICAL PRACTICE NEUROLOGY, 2006, 2 (12): : 658 - 665
  • [83] Spectrum of saccade system function in Alzheimer disease
    Shafiq-Antonacci, R
    Maruff, P
    Masters, C
    Currie, J
    [J]. ARCHIVES OF NEUROLOGY, 2003, 60 (09) : 1272 - 1278
  • [84] OCULOMOTOR ABNORMALITIES IN PARKINSONS-DISEASE
    SHIBASAKI, H
    TSUJI, S
    KUROIWA, Y
    [J]. ARCHIVES OF NEUROLOGY, 1979, 36 (06) : 360 - 364
  • [85] Motor changes in presymptomatic Huntington disease gene carriers
    Siemers, E
    Foroud, T
    Bill, DJ
    Sorbel, J
    Norton, JA
    Hodes, ME
    Niebler, G
    Conneally, PM
    Christian, JC
    [J]. ARCHIVES OF NEUROLOGY, 1996, 53 (06) : 487 - 492
  • [86] A DISORDER OF RAPID EYE MOVEMENTS IN HUNTINGTONS CHOREA
    STARR, A
    [J]. BRAIN, 1967, 90 : 545 - &
  • [87] Electrical stimulation of the posteroventral pallidum influences internally guided saccades in Parkinson's disease
    Straube, A
    Ditterich, J
    Oertel, W
    Kupsch, A
    [J]. JOURNAL OF NEUROLOGY, 1998, 245 (02) : 101 - 105
  • [88] Saccadometry: A novel clinical tool for quantification of the motor effects of subthalamic nucleus stimulation in Parkinson's disease
    Temel, Yasin
    Visser-Vandewalle, Veerle
    Carpenter, Roger H. S.
    [J]. EXPERIMENTAL NEUROLOGY, 2009, 216 (02) : 481 - 489
  • [89] TERAVAINEN H, 1980, ACTA NEUROL SCAND, V62, P149
  • [90] SACCADES IN HUNTINGTONS-DISEASE - PREDICTIVE TRACKING AND INTERACTION BETWEEN RELEASE OF FIXATION AND INITIATION OF SACCADES
    TIAN, JR
    ZEE, DS
    LASKER, AG
    FOLSTEIN, SE
    [J]. NEUROLOGY, 1991, 41 (06) : 875 - 881