Ocular motor abnormalities in neurodegenerative disorders

被引：51
作者：
Antoniades, C. A. [1 ]
Kennard, C. [1 ]
机构：
[1] Univ Oxford, Nuffield Dept Clin Neurosci, Oxford OX3 9DU, England
来源：
EYE | 2015年 / 29卷 / 02期
关键词：
SACCADIC EYE-MOVEMENT; FRONTOTEMPORAL LOBAR DEGENERATION; SUBTHALAMIC NUCLEUS STIMULATION; PROGRESSIVE SUPRANUCLEAR PALSY; MILD COGNITIVE IMPAIRMENT; HUNTINGTON DISEASE GENE; MEMORY-GUIDED SACCADES; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; CORTICOBASAL DEGENERATION;
D O I：
10.1038/eye.2014.276
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Eye movements are a source of valuable information to both clinicians and scientists as abnormalities of them frequently act as clues to the localization of a disease process. Classically, they are divided into two main types: those that hold the gaze, keeping images steady on the retina (vestibulo-ocular and optokinetic reflexes) and those that shift gaze and redirect the line of sight to a new object of interest (saccades, vergence, and smooth pursuit). Here we will review some of the major ocular motor abnormalities present in neurodegenerative disorders.
引用
收藏
页码：200 / 207
页数：8
相关论文
共 99 条
  • [1] Effects of stimulus predictability and interstimulus gap on saccades in Alzheimer's disease
    Abel, LA
    Unverzagt, F
    Yee, RD
    [J]. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2002, 13 (04) : 235 - 243
  • [2] The use of quantitative oculometry in the assessment of Huntington's disease
    Ali, FR
    Michell, AW
    Barker, RA
    Carpenter, RHS
    [J]. EXPERIMENTAL BRAIN RESEARCH, 2006, 169 (02) : 237 - 245
  • [3] Dissociating cognitive deficits involved in voluntary eye movement dysfunctions in Parkinson's disease patients
    Amador, Silvia C.
    Hood, Ashley J.
    Schiess, Mya C.
    Izor, Robert
    Sereno, Anne B.
    [J]. NEUROPSYCHOLOGIA, 2006, 44 (08) : 1475 - 1482
  • [4] Diagnostic potential of saccadometry in progressive supranuclear palsy
    Antoniades, Chrystalina A.
    Bak, Thomas H.
    Carpenter, R. H. S.
    Hodges, John R.
    Barker, Roger A.
    [J]. BIOMARKERS IN MEDICINE, 2007, 1 (04) : 487 - 490
  • [5] Saccadometry: a new tool for evaluating presymptomatic Huntington patients
    Antoniades, Chrystalina A.
    Altham, Pat M. E.
    Mason, Sarah L.
    Barker, Roger A.
    Carpenter, Roger
    [J]. NEUROREPORT, 2007, 18 (11) : 1133 - 1136
  • [6] Deep Brain Stimulation: Eye Movements Reveal Anomalous Effects of Electrode Placement and Stimulation
    Antoniades, Chrystalina A.
    Buttery, Philip
    FitzGerald, James J.
    Barker, Roger A.
    Carpenter, Roger H. S.
    Watts, Colin
    [J]. PLOS ONE, 2012, 7 (03):
  • [7] Huntington's disease: changes in saccades and hand-tapping over 3 years
    Antoniades, Chrystalina A.
    Xu, Zheyu
    Mason, Sarah L.
    Carpenter, R. H. S.
    Barker, Roger A.
    [J]. JOURNAL OF NEUROLOGY, 2010, 257 (11) : 1890 - 1898
  • [8] Control of saccades in Parkinson's disease
    Armstrong, IT
    Chan, F
    Riopelle, RJ
    Munoz, DP
    [J]. BRAIN AND COGNITION, 2002, 49 (02) : 198 - 201
  • [9] OCULOMOTOR DISORDERS IN HUNTINGTONS-CHOREA
    AVANZINI, G
    GIROTTI, F
    CARACENI, T
    SPREAFICO, R
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1979, 42 (07) : 581 - 589
  • [10] Slow vertical saccades in motor neuron disease:: Correlation of structure and function
    Averbuch-Heller, L
    Helmchen, C
    Horn, AKE
    Leigh, RJ
    Büttner-Ennever, JA
    [J]. ANNALS OF NEUROLOGY, 1998, 44 (04) : 641 - 648
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