Ocular motor abnormalities in neurodegenerative disorders

被引：56

作者：

Antoniades, C. A. ^{[1
]}

Kennard, C. ^{[1
]}

机构：

[1] Univ Oxford, Nuffield Dept Clin Neurosci, Oxford OX3 9DU, England

来源：

EYE | 2015年 / 29卷 / 02期

关键词：

SACCADIC EYE-MOVEMENT; FRONTOTEMPORAL LOBAR DEGENERATION; SUBTHALAMIC NUCLEUS STIMULATION; PROGRESSIVE SUPRANUCLEAR PALSY; MILD COGNITIVE IMPAIRMENT; HUNTINGTON DISEASE GENE; MEMORY-GUIDED SACCADES; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; CORTICOBASAL DEGENERATION;

D O I：

10.1038/eye.2014.276

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Eye movements are a source of valuable information to both clinicians and scientists as abnormalities of them frequently act as clues to the localization of a disease process. Classically, they are divided into two main types: those that hold the gaze, keeping images steady on the retina (vestibulo-ocular and optokinetic reflexes) and those that shift gaze and redirect the line of sight to a new object of interest (saccades, vergence, and smooth pursuit). Here we will review some of the major ocular motor abnormalities present in neurodegenerative disorders.

引用

页码：200 / 207

页数：8

共 99 条

[1] Effects of stimulus predictability and interstimulus gap on saccades in Alzheimer's disease [J].

Abel, LA ;

Unverzagt, F ;

Yee, RD .

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2002, 13 (04) :235-243

[2] The use of quantitative oculometry in the assessment of Huntington's disease [J].

Ali, FR ;

Michell, AW ;

Barker, RA ;

Carpenter, RHS .

EXPERIMENTAL BRAIN RESEARCH, 2006, 169 (02) :237-245

[3] Dissociating cognitive deficits involved in voluntary eye movement dysfunctions in Parkinson's disease patients [J].

Amador, Silvia C. ;

Hood, Ashley J. ;

Schiess, Mya C. ;

Izor, Robert ;

Sereno, Anne B. .

NEUROPSYCHOLOGIA, 2006, 44 (08) :1475-1482

[4] Diagnostic potential of saccadometry in progressive supranuclear palsy [J].

Antoniades, Chrystalina A. ;

Bak, Thomas H. ;

Carpenter, R. H. S. ;

Hodges, John R. ;

Barker, Roger A. .

BIOMARKERS IN MEDICINE, 2007, 1 (04) :487-490

[5] Saccadometry: a new tool for evaluating presymptomatic Huntington patients [J].

Antoniades, Chrystalina A. ;

Altham, Pat M. E. ;

Mason, Sarah L. ;

Barker, Roger A. ;

Carpenter, Roger .

NEUROREPORT, 2007, 18 (11) :1133-1136

[6] Deep Brain Stimulation: Eye Movements Reveal Anomalous Effects of Electrode Placement and Stimulation [J].

Antoniades, Chrystalina A. ;

Buttery, Philip ;

FitzGerald, James J. ;

Barker, Roger A. ;

Carpenter, Roger H. S. ;

Watts, Colin .

PLOS ONE, 2012, 7 (03)

[7] Huntington's disease: changes in saccades and hand-tapping over 3 years [J].

Antoniades, Chrystalina A. ;

Xu, Zheyu ;

Mason, Sarah L. ;

Carpenter, R. H. S. ;

Barker, Roger A. .

JOURNAL OF NEUROLOGY, 2010, 257 (11) :1890-1898

[8] Control of saccades in Parkinson's disease [J].

Armstrong, IT ;

Chan, F ;

Riopelle, RJ ;

Munoz, DP .

BRAIN AND COGNITION, 2002, 49 (02) :198-201

[9] OCULOMOTOR DISORDERS IN HUNTINGTONS-CHOREA [J].

AVANZINI, G ;

GIROTTI, F ;

CARACENI, T ;

SPREAFICO, R .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1979, 42 (07) :581-589

[10] Slow vertical saccades in motor neuron disease:: Correlation of structure and function [J].

Averbuch-Heller, L ;

Helmchen, C ;

Horn, AKE ;

Leigh, RJ ;

Büttner-Ennever, JA .

ANNALS OF NEUROLOGY, 1998, 44 (04) :641-648

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