The role of dendritic cell subsets in immunity to viruses

被引：36

作者：

Carbone, FR ^{[1
]}

Heath, WR

机构：

[1] Univ Melbourne, Dept Microbiol & Immunol, Parkville, Vic 3010, Australia

[2] Walter & Eliza Hall Inst Med Res, Div Immunol, Parkville, Vic 3050, Australia

来源：

CURRENT OPINION IN IMMUNOLOGY | 2003年 / 15卷 / 04期

关键词：

D O I：

10.1016/S0952-7915(03)00074-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Dendritic cells orchestrate the adaptive immune response. As well as presenting MHC-restricted antigen for T-cell activation, they provide all the co-receptor signals required for full T-cell priming. As a consequence, they play a central role in the immune response to infections caused by many pathogenic agents, including viruses. In recent times, it has become apparent that dendritic cells represent a particularly heterogeneous population with individual subsets playing specialized roles in response to infection.

引用

页码：416 / 420

页数：5

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