Solvent-free synthesis of nitrilotriacetamide and diketopiperazines from nitrilotriacetic acid under microwave irradiation and their antimicrobial activity

被引：5

作者：

Oeztuerk, Guelsen ^{[1
]}

Guemguem, Bahattin ^{[1
]}

Kizil, Murat ^{[1
]}

Emen, Sevil ^{[1
]}

机构：

[1] Dicle Univ, Dept Chem, Fac Sci & Art, TR-21280 Diyarbakir, Turkey

来源：

SYNTHETIC COMMUNICATIONS | 2007年 / 37卷 / 22-24期

关键词：

amide; antimicrobial activity; diketopiperazine; microwave irradiation; solvent-free synthesis;

D O I：

10.1080/00397910701572795

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient synthesis of dioxopiperazines-diketopiperzines (DKPs)- and amide from nitrilotriacetic acid (NTA) using microwave irradiation and classical heating were described. All compounds were characterized using H-1 NMR, C-13 NMR and elemental analysis. Antimicrobial effects of these compounds are also investigated. All tested compounds showed moderate antimicrobial activity.

引用

页码：3981 / 3988

页数：8

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