Treatment Outcomes of Patients Switching From an Injectable Drug to Bedaquiline During Short Standardized Treatment for Multidrug-resistant Tuberculosis in Mozambique

被引:7
|
作者
Bastard, Mathieu [1 ]
Molfino, Lucas [2 ]
Mutaquiha, Claudia [3 ]
Galindo, Miriam Arago [2 ]
Zindoga, Pereira [3 ]
Vaz, Deise [2 ]
Mahinca, Ivan [3 ]
DuCros, Philipp [4 ]
Rusch, Barbara [5 ]
Telnov, Alex [5 ]
机构
[1] Epictr, 8 Rue St Sabin, F-75011 Paris, France
[2] Med Sans Frontieres, Maputo, Mozambique
[3] Minis Hlth, Maputo, Mozambique
[4] Burnet Inst, Melbourne, Australia
[5] Med Sans Frontieres, Geneva, Switzerland
关键词
multidrug-resistant tuberculosis; short regimen; bedaquiline; treatment outcomes; injectable drugs;
D O I
10.1093/cid/ciz196
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Bedaquiline was recommended by the World Health Organization as the preferred option in treatment of multidrug-resistant tuberculosis (MDR-TB) with long regimens. However, no recommendation was given for the short MDR-TB regimen. Data from our small cohort of patients who switched from injectable drug to bedaquiline suggest that a bedaquiline-based short regimen is effective and safe.
引用
收藏
页码:1809 / 1811
页数:3
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