A fluorescence sensing platform with the MnO2 nanosheets as an effective oxidant for glutathione detection

被引：46
作者：
Yao, Cuiping [1 ]
Wang, Jing [1 ]
Zheng, Aixian [2 ,3 ]
Wu, Lingjie [2 ,3 ]
Zhang, Xiaolong [2 ,3 ]
Liu, Xiaolong [2 ,3 ]
机构：
[1] Xi An Jiao Tong Univ, Inst Biomed Analyt Technol & Instrumentat, Sch Life Sci & Technol, Key Lab Biomed Informat Engn,Minist Educ, Xian 710049, Shaanxi, Peoples R China
[2] Fujian Med Univ, United Innovat Mengchao Hepatobiliary Technol Key, Mengchao Hepatobiliary Hosp, Fuzhou 350025, Fujian, Peoples R China
[3] Fujian Med Univ, Liver Ctr Fujian Prov, Fuzhou 350025, Fujian, Peoples R China
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 2017年 / 252卷
基金：
中国国家自然科学基金;
关键词：
Glutathione; Manganese dioxide nanosheets; O-phenylenediamine; Redox reaction; Oxidation; CELLULAR GLUTATHIONE; PROBE; BIOTHIOLS; NANOPARTICLES; THIOLS; ENZYME; ASSAY;
D O I：
10.1016/j.snb.2017.05.136
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Herein, a sensitive, selective, rapid and cost-effective fluorescence sensing platform has been designed for the detection of glutathione (GSH). In this platform, the manganese dioxide (Mn0(2))nanosheets served as both oxidant, which could effectively oxidize o-phenylenediamine (OPDA) to produce fluorescence for highly sensitive detection, and recognition element. When GSH was introduced, the Mn02 nanosheets were reduced to Mn2+, which inhibited the formation of fluorescent oxidation products of OPDA. Under optimal conditions, the Mn0(2)-OPDA sensing platform showed very sensitive response to GSH in the range of 10 nM-40 mu M. The detection limit of GSH reached as low as 10 nM. The high selectivity of inhibition of fluorescent product formation by GSH allows this platform to be used for detecting GSH in practical biological samples (such as cell extracts). (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码：30 / 36
页数：7
相关论文
共 33 条
[1]   A rapid fluorescence "switch-on" assay for glutathione detection by using carbon dots-MnO2 nanocomposites [J].
Cai, Qi-Yong ;
Li, Jie ;
Ge, Jia ;
Zhang, Lin ;
Hu, Ya-Lei ;
Li, Zhao-Hui ;
Qu, Ling-Bo .
BIOSENSORS & BIOELECTRONICS, 2015, 72 :31-36
[2]   Break-up of Two-Dimensional MnO2 Nanosheets Promotes Ultrasensitive pH-Triggered Theranostics of Cancer [J].
Chen, Yu ;
Ye, Delai ;
Wu, Meiying ;
Chen, Hangrong ;
Zhang, Linlin ;
Shi, Jianlin ;
Wang, Lianzhou .
ADVANCED MATERIALS, 2014, 26 (41) :7019-+
[3]   Regulation of gene expression by reactive oxygen [J].
Dalton, TD ;
Shertzer, HG ;
Puga, A .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1999, 39 :67-101
[4]   Intracellular Glutathione Detection Using MnO2-Nanosheet-Modified Upconversion Nanoparticles [J].
Deng, Renren ;
Xie, Xiaoji ;
Vendrell, Marc ;
Chang, Young-Tae ;
Liu, Xiaogang .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (50) :20168-20171
[5]   Cellular glutathione and thiols metabolism [J].
Dickinson, DA ;
Forman, HJ .
BIOCHEMICAL PHARMACOLOGY, 2002, 64 (5-6) :1019-1026
[6]   A Smart DNAzyme-MnO2 Nanosystem for Efficient Gene Silencing [J].
Fan, Huanhuan ;
Zhao, Zilong ;
Yan, Guobei ;
Zhang, Xiaobing ;
Yang, Chao ;
Meng, Hongmin ;
Chen, Zhuo ;
Liu, Hui ;
Tan, Weihong .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (16) :4801-4805
[7]   Ultrasensitive Glutathione Detection Based on Lucigenin Cathodic Electrochemiluminescence in the Presence of MnO2 Nanosheets [J].
Gao, Wenyue ;
Liu, Zhongyuan ;
Qi, Liming ;
Lai, Jianping ;
Kitte, Shimeles Addisu ;
Xu, Guobao .
ANALYTICAL CHEMISTRY, 2016, 88 (15) :7654-7659
[8]   A sensitive turn-on fluorescent probe for intracellular imaging of glutathione using single-layer MnO2 nanosheet-quenched fluorescent carbon quantum dots [J].
He, Dinggeng ;
Yang, Xiaoxiao ;
He, Xiaoxiao ;
Wang, Kemin ;
Yang, Xue ;
He, Xing ;
Zou, Zhen .
CHEMICAL COMMUNICATIONS, 2015, 51 (79) :14764-14767
[9]   Disulfide-Cleavage-Triggered Chemosensors and Their Biological Applications [J].
Lee, Min Hee ;
Yang, Zhigang ;
Lim, Choon Woo ;
Lee, Yun Hak ;
Dongbang, Sun ;
Kang, Chulhun ;
Kim, Jong Seung .
CHEMICAL REVIEWS, 2013, 113 (07) :5071-5109
[10]   Electrochemical determination of free and total glutathione in human saliva samples [J].
Lee, Patricia T. ;
Goncalves, Luis M. ;
Compton, Richard G. .
SENSORS AND ACTUATORS B-CHEMICAL, 2015, 221 :962-968
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