Supportive care of right ventricular failure due to fat embolism syndrome

被引:4
作者
Schwalbach, Kevin T. [1 ]
Wade, R. Chad [2 ,3 ]
Mkorombindo, Takudzwa [2 ,3 ]
McElwee, Sam K. [4 ]
Wells, J. Michael [2 ,3 ,5 ]
Wille, Keith M. [2 ]
机构
[1] Univ Alabama Birmingham, Dept Med, Birmingham, AL 35294 USA
[2] Univ Alabama Birmingham, Div Pulm Allergy & Crit Care Med, Birmingham, AL USA
[3] UAB Lung Hlth Ctr, Birmingham, AL USA
[4] Univ Alabama Birmingham, Div Cardiovasc Dis, Birmingham, AL 35294 USA
[5] Birmingham VA Med Ctr, Birmingham, AL USA
关键词
Fat embolism; Right ventricle; Pulmonary hypertension; Hypoxemia; PULMONARY-EMBOLISM; MANAGEMENT;
D O I
10.1016/j.rmcr.2021.101499
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Pulmonary fat embolism is a common phenomenon in cases of traumatic long bone fractures, with only a minority developing the more catastrophic Fat Embolism Syndrome (FES). Diagnosis is clinical and requires a high index of suspicion. Treatment remains under-investigated, with common interventions having low quality levelof-evidence and no mortality benefit. In severe cases, focus should be on supporting the failing right ventricle through use of inotropes, pulmonary vasodilators, and mechanical circulatory support. This requires a thorough understanding of the unique physiology through the pulmonary circulation.
引用
收藏
页数:5
相关论文
共 15 条
[1]   ECMO and Right Ventricular Failure: Review of the Literature [J].
Grant, Christian, Jr. ;
Richards, Jeremy B. ;
Frakes, Michael ;
Cohen, Jason ;
Wilcox, Susan R. .
JOURNAL OF INTENSIVE CARE MEDICINE, 2021, 36 (03) :352-360
[2]   A Critical Review of Hemodynamically Guided Therapy for Cardiogenic Shock: Old Habits Die Hard [J].
Isseh, Iyad N. ;
Lee, Ran ;
Khedraki, Rola ;
Hoffman, Karlee .
CURRENT TREATMENT OPTIONS IN CARDIOVASCULAR MEDICINE, 2021, 23 (05)
[3]   Fat Embolism Syndrome [J].
Kosova, Ethan ;
Bergmark, Brian ;
Piazza, Gregory .
CIRCULATION, 2015, 131 (03) :317-320
[4]   High-resolution CT findings in mild pulmonary fat embolism [J].
Malagari, K ;
Economopoulos, N ;
Stoupis, C ;
Daniil, Z ;
Papiris, S ;
Müller, NL ;
Kelekis, D .
CHEST, 2003, 123 (04) :1196-1201
[5]   Acute Right Ventricular Failure in the Setting of Acute Pulmonary Embolism or Chronic Pulmonary Hypertension: A Detailed Review of the Pathophysiology, Diagnosis, and Management [J].
Matthews, Jennifer Cowger ;
McLaughlin, Vallerie .
CURRENT CARDIOLOGY REVIEWS, 2008, 4 (01) :49-59
[6]   Fat embolism [J].
Mellor, A ;
Soni, N .
ANAESTHESIA, 2001, 56 (02) :145-154
[7]  
Muller C, 1994, Orthop Rev, V23, P107
[8]  
Ong Sidney Ching Liang, 2017, BMJ Case Rep, V2017, DOI 10.1136/bcr-2017-223007
[9]   Advanced Management of Intermediate- and High-Risk Pulmonary Embolism JACC Focus Seminar [J].
Piazza, Gregory .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 76 (18) :2117-2127
[10]   Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review [J].
Price, Laura C. ;
Wort, Stephen J. ;
Finney, Simon J. ;
Marino, Philip S. ;
Brett, Stephen J. .
CRITICAL CARE, 2010, 14 (05)