Comprehensive profiling of H-Ras signalling in angiosarcoma endothelium

被引：6

作者：

da Costa, A. ^{[1
]}

Bonner, M. ^{[1
]}

Arbiser, J. L. ^{[1
]}

机构：

[1] Emory Univ, Sch Med, Dept Med, Atlanta, GA USA

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 2017年 / 42卷 / 06期

关键词：

CUTANEOUS ANGIOSARCOMA; ANGIOGENESIS; CANCER;

D O I：

10.1111/ced.13149

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The MS1/SVR system, in which MS1 represents immortalized endothelial cells and SVR represents MS1 cells transformed with oncogenic human-rat sarcoma protein (H-Ras), has been used for around 20 years as a valuable tool to study angiogenesis and carcinogenesis. Despite the use of these cells in numerous studies, a comprehensive profile of the signalling differences due to oncogenic H-Ras transformation has not been performed previously. In this study, we profiled the well-known MS1 and SVR cell lines using a combination of both Western blot and gene chip assays.

引用

收藏

页码：645 / 647

页数：3

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