Convenient synthesis of some optically active 1,4-benzodiazepin-2,5-diones

被引：3
作者：
Bakavoli, M. [1 ]
Davoodnia, A. [1 ]
Shahnaee, R. [1 ]
机构：
[1] Islamic Azad Univ, Sch Sci, Dept Chem, Mashhad Branch, Tehran, Iran
来源：
CHINESE CHEMICAL LETTERS | 2008年 / 19卷 / 01期
关键词：
L-amino acids; benzodiazepinone; optically active; phosphoryl chloride; heterocycles;
D O I：
10.1016/j.cclet.2007.10.043
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Isatoic anhydride was reacted with several L-amino acids to give the corresponding (2S)-N-(o-aminobenzoyl)-2-alkyl-aminoacetic acids. The latter compounds were treated with phosphoryl chloride under reflux temperature to afford the cyclized products, (3S)-3-alkyl-3,4-dihydro-1H-1,4-benzodiazepin-2,5-diones. (C) 2007 M. Bakavoli. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：12 / 14
页数：3
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