Arterio-venous gradient of endothelial progenitor cells across renal artery stenosis

被引：10

作者：

Fadini, GP

Miotto, D

Baesso, I

Facco, M

Miorin, M

Tiengo, A

Agostini, C

Avogaro, A

机构：

[1] Univ Padua, Sch Med, Div Metab Dis, Dept Clin & Expt Med, I-35128 Padua, Italy

[2] Univ Padua, Sch Med, Dept Clin & Expt Med, Clin Immunol & Hematol, I-35128 Padua, Italy

[3] Univ Padua, Sch Med, Inst Radiol, I-35128 Padua, Italy

来源：

ATHEROSCLEROSIS | 2005年 / 182卷 / 01期

关键词：

arterio-venous; endothelial progenitor cells; renal artery stenosis;

D O I：

10.1016/j.atherosclerosis.2005.04.010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A role for circulating progenitor cells have been recently demonstrated in many pathological conditions. Endothelial progenitor cells (EPCs) localize at sites of ischemia and stimulate neovasculogenesis. This small study was carried out to assess whether selective blood sampling during renal angiography could demonstrate an arterio-venous gradient of EPCs in 5 patients with renal artery stenosis. Surprisingly, we found that EPCs were more abundant in venous than in arterial blood, suggesting that the kidney subjected to chronic ischemia may become a source rather than a target of EPCs. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：189 / 191

页数：3

共 7 条

[1] Isolation of putative progenitor endothelial cells for angiogenesis [J].