High frequency of BRCA1/2 and p53 somatic inactivation in sporadic ovarian cancer

被引：3
作者：
Zikan, Michal
Janatova, Marketa
Pavlista, David
Pohlreich, Petr
机构：
[1] Charles Univ Prague, Dept Biochem & Expt Oncol, Fac Med 1, Prague 12853 2, Czech Republic
[2] Charles Univ Prague, Clin Obstet & Gynaecol, Fac Med 1, Prague 12853 2, Czech Republic
[3] Gen Teaching Hosp, Prague 12853 2, Czech Republic
来源：
JOURNAL OF GENETICS | 2007年 / 86卷 / 02期
关键词：
BRCA1; BRCA2; p53; sporadic ovarian cancer; loss of heterozygosity;
D O I：
10.1007/s12041-007-0022-y
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
[No abstract available]
引用
收藏
页码：169 / 171
页数：3
相关论文
共 14 条
[1]  
Chan KYK, 2002, CANCER RES, V62, P4151
[2]   Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors [J].
Esteller, M ;
Silva, JM ;
Dominguez, G ;
Bonilla, F ;
Matias-Guiu, X ;
Lerma, E ;
Bussaglia, E ;
Prat, J ;
Harkes, IC ;
Repasky, EA ;
Gabrielson, E ;
Schutte, M ;
Baylin, SB ;
Herman, JG .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (07) :564-569
[3]  
Geisler JP, 2002, JNCI-J NATL CANCER I, V94, P61
[4]  
Gras E, 2001, CANCER-AM CANCER SOC, V92, P787, DOI 10.1002/1097-0142(20010815)92:4<787::AID-CNCR1384>3.0.CO
[5]  
2-4
[6]  
Hilton JL, 2002, JNCI-J NATL CANCER I, V94, P1396
[7]  
Janatová M, 2003, NEOPLASMA, V50, P246
[8]   The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer [J].
Marcia L McCoy ;
Christopher R Mueller ;
Calvin D Roskelley .
Reproductive Biology and Endocrinology, 1 (1)
[9]   Promoter hypermethylation and post-transcriptional mechanisms for reduced BRCA1 immunoreactivity in sporadic human breast cancers [J].
Miyamoto, K ;
Fukutomi, T ;
Asada, K ;
Wakazono, K ;
Tsuda, H ;
Asahara, T ;
Sugimura, T ;
Ushijima, T .
JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2002, 32 (03) :79-84
[10]   Mutations of the BRCA1 gene in hereditary breast and ovarian cancer in the Czech Republic [J].
Pohlreich, P ;
Stríbrná, J ;
Kleibl, Z ;
Zikán, M ;
Kalbácová, R ;
Petruzelka, L ;
Konopásek, B .
MEDICAL PRINCIPLES AND PRACTICE, 2003, 12 (01) :23-29
12