Effects of granulocyte colony-stimulating factor administration time on pain

被引：1

作者：

Ozkaraman, A. ^{[1
]}

Argon, G. ^{[1
,2
]}

Yesilbalkan, Usta O. ^{[1
,2
]}

Dugum, O. ^{[1
,3
]}

Yigitaslan, S. ^{[1
,4
]}

Musmul, A. ^{[1
,5
]}

Alparslan, Balci G. ^{[1
]}

机构：

[1] Eskisehir Osmangazi Univ, Fac Hlth Sci, Dept Nursing, Meselik Campus, TR-26480 Odunpazari, Eskisehir, Turkey

[2] Ege Univ, Fac Nursing, Izmir, Turkey

[3] Eskisehir Special Umit Batikent Hosp, Eskisehir, Turkey

[4] Eskisehir Osmangazi Univ, Fac Med, Dept Pharmacol, Eskisehir, Turkey

[5] Eskisehir Osmangazi Univ, Fac Med, Dept Biostat, Eskisehir, Turkey

来源：

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY | 2017年 / 118卷 / 07期

关键词：

cancer; G-CSF; pain; nurse; INDUCED BONE PAIN; RECEIVING CHEMOTHERAPY; CLINICAL-TRIAL; PEGFILGRASTIM; NEUTROPENIA; PREVENTION; EXERCISE; RHYTHMS;

D O I：

10.4149/BLL_2017_078

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE: This study was aimed at evaluating the effect of administration time of granulocyte colony-stimulating factor (G-CSF) on the level of pain related to G-CSF. METHODS: This study was carried out with 48 cancer patients divided into A and B groups. In the first stage of the study, the groups A and B were planned to be administered with G-CSF at 10: 00 and 14: 00, respectively. In the second stage, patients in groups A and B were asked to self-administer filgrastim at 14: 00 and 10: 00, respectively. Patients were also asked to assess their pain level after G-CSF administration for a total of 4 times. RESULTS: According to the findings, the incidence of pain related to G-CSF was 91.7 %. The pain score after G-CSF being administered at 10: 00 was significantly higher compared to administration at 14: 00 in both groups (group A after 4, 8, and 12 hours: p < 0.05; group B after 4 and 8 hours: p < 0.05). CONCLUSIONS: The results of the present study have demonstrated that the pain score related to G-CSF administration at 14:00 p.m. was significantly reduced. Thus, in order to minimize the pain, it will be more beneficial to administer G-CSF at 14: 00 (Tab. 4, Ref. 31). Text in PDF www.elis.sk.

引用

页码：399 / 404

页数：6

共 31 条

[1] Bone pain from granulocyte colony stimulating factor: does clinical trial sponsorship by a pharmaceutical company influence its reporting? [J].