Recently, the triboelectric nanogenerator (TENG) has become a well-known energy harvester for ambient-resource energy harvesting for which the contact electrification between two different materials is employed. Alternatively, research has been carried out on the fluid-based TENG (FluTENG) for the replacement of the conventional solid-based TENG due to the destruction of the active surface by a long mechanical rupture that reduces the triboelectrical effect. For the first time, a simple, eco-friendly, very economical, and novel DI (deionized)-water commercial-polytetrafluoroethylene (cPTFE)-based FluTENG with contact-separation (CS-FluTENG) and lateral-sliding (LS-FluTENG) modes has been developed for this paper. Here, we examined the dynamic interaction between water and solid contact for each mode. During the study of the surface morphologies for both the CS-FluTENG and the LS-FluTENG, an FE-SEM analysis showed expansions of the fibril lengths in the film network. Also, the mechanistic approach of water splitting and the way that a chemical reaction occurs with the cPTFE film during the contact electrification that have been proved by UV-spectroscopy, FT-IR, and XRD analyses were investigated in this manuscript. The contact-angle measurements revealed that the surface-hydrophobicity values of the films were decreased after the CS-FluTENG and LS-FluTENG experiments due to a roughness increment, and the fibril distance from the nodes was increased. The triboelectric-power density values reached up to 2.15 mW/m(2) for the CS-FluTENG and 0.8 mW/m(2) for the LS-FluTENG, respectively. Moreover, the instantaneous power reached up to 2.4 mu W for the CS-FluTENG and 1.85 mu W for the LS-FluTENG, respectively. [GRAPHICS] .