A new system for long-term monitoring of gait in Parkinson's disease (PD) has been developed and validated. The characteristics of every stride taken over 10-h epochs were acquired using a lightweight ankle-mounted sensor array that transmitted data wirelessly to a small pocket PC at a rate of 100 Hz. Stride was calculated from the vertical linear acceleration and pitch angular velocity of the leg with an accuracy of 5 cm. Results from PD patients (5) demonstrate the effectiveness of long-term monitoring of gait in a natural environment. The small, variable stride length characteristic of Parkinsonian gait, and fluctuations of efficacy associated with levodopa therapy, such as delayed onset, wearing off, and the 'off/on' effect, could reliably be detected from long-term changes in stride length. (c) 2006 Elsevier B.V. All rights reserved.
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Rabin Med Ctr, Dept Neurol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Neurol, Petah Tiqwa, Israel
Yust-Katz, Shlomit
Sthneer, Sonia
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Rabin Med Ctr, Dept Neurol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Neurol, Petah Tiqwa, Israel
Sthneer, Sonia
Melamed, Eldad
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Rabin Med Ctr, Dept Neurol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Neurol, Petah Tiqwa, Israel
Melamed, Eldad
Djaldetti, Ruth
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Rabin Med Ctr, Dept Neurol, Petah Tiqwa, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelRabin Med Ctr, Dept Neurol, Petah Tiqwa, Israel
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Seoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea
Republ Korea Air Force, Aerosp Med Ctr, Dept Neurol, Cheongju, Chungcheongbuk, South KoreaSeoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea
Kim, Ryul
Kim, Han-Joon
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Seoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South KoreaSeoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea
Kim, Han-Joon
Shin, Chaewon
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Kyung Hee Univ Hosp, Dept Neurol, Seoul, South KoreaSeoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea
Shin, Chaewon
Park, Hyeyoung
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Seoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South KoreaSeoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea
Park, Hyeyoung
Kim, Aryun
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Seoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South KoreaSeoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea
Kim, Aryun
Ha Paek, Sun
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Seoul Natl Univ Hosp, Coll Med, Dept Neurosurg, Seoul, South KoreaSeoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea
Ha Paek, Sun
Jeon, Beomseok
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Seoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South KoreaSeoul Natl Univ Hosp, Coll Med, Dept Neurol, Seoul, South Korea
机构:
St Joseph Hosp Berlin Weissensee, Dept Neurol, Gartenstr 1, D-13088 Berlin, GermanySt Joseph Hosp Berlin Weissensee, Dept Neurol, Gartenstr 1, D-13088 Berlin, Germany
Mueller, Thomas
Moehr, Jan-Dominique
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St Joseph Hosp Berlin Weissensee, Dept Neurol, Gartenstr 1, D-13088 Berlin, GermanySt Joseph Hosp Berlin Weissensee, Dept Neurol, Gartenstr 1, D-13088 Berlin, Germany